ID A0A158P427_ATTCE Unreviewed; 1587 AA.
AC A0A158P427;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN Name=105627870 {ECO:0000313|EnsemblMetazoa:XP_012064535.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012064535.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012064535.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; ADTU01008287; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01008288; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01008289; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01008290; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012064535.1; XM_012209145.1.
DR EnsemblMetazoa; XM_012209145.1; XP_012064535.1; LOC105627870.
DR GeneID; 105627870; -.
DR KEGG; acep:105627870; -.
DR eggNOG; KOG0059; Eukaryota.
DR InParanoid; A0A158P427; -.
DR OrthoDB; 6951at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF36; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 ISOFORM X1; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005205};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 936..954
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1089..1114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1135..1160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1172..1197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1209..1230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1236..1258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1279..1305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 516..752
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1370..1583
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1587 AA; 179272 MW; 5535F8DB84C93119 CRC64;
MNSCALYFSQ LRAMLVRNLL LKKRDTRKTF MEVVLPLYIL GTLIVVKVMI PNPNFPAMLT
QRHEGDIFEL FNGYKNNTIA VVPNSTETLS FLSSMNSLWL SMWDYPGKLP LNFMVFDTKD
DLQAAYWRDP YSIPLAVIFE DPQPISQRLI YEIRTNPSYV LPPSPTELYS APISCRKNKT
GHWMDDLLSI KTGESCPANN YLHSGFLALQ VMMDITKIRF INPGNPDVTV PDIKLIMFPK
EAYTADWMLA FRVVIPLYMV FALSQFITYL LILIVGEKEN KIKEGMKMMG LNDSVFWLSW
FIIYSIFVFL LSAVGVVLLF TLQMFQHTHF LPIFLLVVLY SFSVIMFAFM ITPFFDKSRT
AGVLGNFAVT TLSLMYFIQV FVSDSSSVTY WLVSLISPTA FALAMDKSLV LDLQGEGVNF
DNLWSGPGIP FGGSLIMMTL DIFLYGYLAY YLDSVIPSEH GTKRPPWFCF LPGFWCQKKV
QRVPSSNGES NSFIPGEEAN RDVEPVVREM KGREAIRIAD LYKSFHKCRQ PEIKAVNGIN
LTIYEGQITA ILGHNGAGKT TLFNILTGLT APTSGTALIF GYDVRDSNDM RAIRSMTGVC
PQHDILFDLL TPREHLEFFA AVRGIPRSMI RHEVKKTLKD IDLVEKADTF ARYLSGGQKR
KLSVGIAIIG DPKIIILDEP TAGVDPYSRR QLWSLLQSRR HGKVILLTTH FMDEADILAD
RKAVISKGRL RCCGSSLFLK NKFGIGYHLT LVLEGNAREH AISRLVTSHV SKAEKARRHG
RELSFILPHN SVENFAPLFS AIEHEIKTRS SRLGISSYGV SMTTLEEVFL HLEKDEETEC
TMDNLSKKMV RNRALSRSLS LQSKSTSYQS LQNEGVIIQG DSQGKANDLP DGIHNDRNPP
VLGLGLDAIK IRPNFFQILY AMLRIRVLRL FRNLQLLYFT IVTPLALVAL GLYLNSIRTV
DVKMESLKLD SHTYNETKIL YLNNTDHDIT KLIDSITQDT KLIEEYDGNF ANLMNIAPHI
AAFNINDYNL PRLNLTVTYN DTMQHSLPIL INILSNAYYR LISGKNEATP IEVHTHPFQQ
TSQPQQFNIG AASCAIFLGM VFIILPITLA VDMVNDREIK AKNQLRVNGL SFSTYFFSYF
IVLVGLMIFI CLCILGIIFL FDVPSLREIP AIITLGILIM LYCPSSIVFS TCLSYIFDKV
DSAQSMLPNI ATFFGLLPFI LVMILDMQGL GGTASFALHV AFSLLNSMYV PYAAVYYVDR
VHLMCSINAA CHYLAMSDYL TMEIILLAFG ALLQCPVWFI VLLILDINKS GGNVSDVFKH
YFLRDGNSIR EEIMENSDIG EHEDTDVKNE RQKVFNFVVS PALSQEPPLV LLQNLRKEYR
QKESGSSCCP KREDERKIAV RNLSLAVEPG EVLGLLGHNG AGKTTAMKII IAEEAPTKGR
VQISGHNINT HMTEAFRQMG YCPQHDAQWK NITVREHLEC YAAIRGVPWS EVDRIVDQYL
TGLQIHEHAD KQSQECSGGT KRKLSFAMAM VSGPKVILMD EPSTGMDPRS KRFLWDTILA
SFQLELDIEE YSFSQTTLEQ VFLKFSH
//
