ID A0A158PLD3_ANGCS Unreviewed; 634 AA.
AC A0A158PLD3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Notch {ECO:0000313|WBParaSite:ACOC_0001121901-mRNA-1};
GN ORFNames=ACOC_LOCUS11220 {ECO:0000313|EMBL:VDM62805.1};
OS Angiostrongylus costaricensis (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0001121901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ACOC_0001121901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM62805.1, ECO:0000313|Proteomes:UP000267027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Costa Rica {ECO:0000313|EMBL:VDM62805.1,
RC ECO:0000313|Proteomes:UP000267027};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; UYYA01004641; VDM62805.1; -; Genomic_DNA.
DR STRING; 334426.A0A158PLD3; -.
DR WBParaSite; ACOC_0001121901-mRNA-1; ACOC_0001121901-mRNA-1; ACOC_0001121901.
DR OMA; RPEVCAK; -.
DR Proteomes; UP000050601; Unplaced.
DR Proteomes; UP000267027; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 3.30.70.3310; -; 1.
DR Gene3D; 4.10.470.20; -; 2.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR035993; Notch-like_dom_sf.
DR InterPro; IPR000800; Notch_dom.
DR PANTHER; PTHR24044:SF420; NEUROGENIC LOCUS PROTEIN DELTA; 1.
DR PANTHER; PTHR24044; NOTCH LIGAND FAMILY MEMBER; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF00066; Notch; 2.
DR PRINTS; PR01452; LNOTCHREPEAT.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 1.
DR SMART; SM00004; NL; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF90193; Notch domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS50258; LNR; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000267027};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..634
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040569038"
FT DOMAIN 52..88
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 90..132
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 157..189
FT /note="LNR"
FT /evidence="ECO:0000259|PROSITE:PS50258"
FT DOMAIN 197..241
FT /note="LNR"
FT /evidence="ECO:0000259|PROSITE:PS50258"
FT REPEAT 543..575
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 398..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 56..66
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 78..87
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 122..131
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 634 AA; 70246 MW; D6FF5FF2D15BDBCA CRC64;
MILRILLVFL LRSAFGDREL SRCPYDFVCH NGLCDSNERC QCTPGWTGEQ CEVELCPSYP
CVNGYCNATE DGRKTCQCDH RFEGQYCELD RDECTLRPCP ADAECVNHVA KHKKDKGYSC
LCPIGYTGEF CEVEGENYCY NGGICDARYV CICEDGCPER PEVCAKVFDN GQCDEVCNRE
SCLFDGFDCV KHDDFVCRNP SDCAYKYGDG HCDDDCAGAE CGFDGGDCNG SKNTFRGRNV
NIIGVALGLP PDVAVKNLRQ LQAELAQWCY SIIPACVLKS FCQRLYTHVS LAQDVDGVMV
YEWSSDHGQG NRVVLNEELA SAIQTTATGT IIFFDVDTSA CRLKIRRNNS QPHCFTDLRA
AATYLALELT RFRPISGKTL PIRDVTWKQK QIVGYPGCSY QPPTPPYSAS PENGNNEEYS
HSKDAENSLA PIIDAESPLL SAVRRGDLKA VKEMISSKEA FMDTLFERNA AGQSPLLFAA
RMAHPGLECI SILVSSIIAI RRHRHDDVLS GHFSDIGNSR AELIKSLPLH DEGDVKYALT
DSMGDAPIHL AARGGNVEAV VALIHNNCDL TAKDAFGMFS TSPCQEYDGF CRLYQNGGQA
SSRVVLSRSP LPSDEQNSLI AFYMDDYREF WKPE
//
