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Database: UniProt
Entry: A0A158Q797_9BILA
LinkDB: A0A158Q797_9BILA
Original site: A0A158Q797_9BILA 
ID   A0A158Q797_9BILA        Unreviewed;      5055 AA.
AC   A0A158Q797;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   10-MAY-2017, entry version 9.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|WBParaSite:EEL_0000393501-mRNA-1};
OS   Elaeophora elaphi.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Spirurida;
OC   Filarioidea; Onchocercidae; Elaeophora.
OX   NCBI_TaxID=1147741 {ECO:0000313|WBParaSite:EEL_0000393501-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000050640, ECO:0000313|WBParaSite:EEL_0000393501-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:EEL_0000393501-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
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DR   WBParaSite; EEL_0000393501-mRNA-1; EEL_0000393501-mRNA-1; EEL_0000393501.
DR   Proteomes; UP000050640; Genome Assembly.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00054; EFh; 2.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 2.
DR   PROSITE; PS00018; EF_HAND_1; 2.
DR   PROSITE; PS50222; EF_HAND_2; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Calcium {ECO:0000256|PROSITE-ProRule:PRU00448};
KW   Complete proteome {ECO:0000313|Proteomes:UP000050640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050640};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4606   4623       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4669   4691       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4807   4829       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4849   4874       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4934   4953       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      104    164       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      171    215       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      224    279       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      285    344       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      349    407       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      586    807       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1026   1220       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     4165   4200       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   DOMAIN     4203   4235       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   CA_BIND    4178   4189       {ECO:0000256|PROSITE-ProRule:PRU00448}.
FT   CA_BIND    4213   4224       {ECO:0000256|PROSITE-ProRule:PRU00448}.
SQ   SEQUENCE   5055 AA;  574539 MW;  90857C75DAA349D3 CRC64;
     MTDKEGAGDG EQDDISFLRT GDIVAMTCMA SANREGVLGS ERVCLCTEGF GNRMCSLENV
     SDRDLPPDIS MCMLYIDNAL SVRALQEMMS NDKELRGAGS GGGHKTLLYG HAVQLKHVQS
     EMVSLNLLYL ACLSSCSSND KLAFDVGVQE NNEGEACWWT IHPASKQRSE GEKVRVGDDV
     ILVSVATERY LHMTHSKGFM VIASFHQTLW NITSVSSGSV RMRNMGALFG NDVLRFFHGN
     DEVLTIPENW SEHPQHNMAI YEGGAAVSQA RSLWRIELIR GKWHGALVGW EQPFRIRHIT
     SGRYLGVMEN VIQLYDKDKA ELDTTAFVMY QIKDTKKQLT EEKEEGMGVA TIRYGETNAF
     IQHIKTELWL SYQTSEITKK GLGKVEEKKA VALKDGHMDD CFTFFMALEE ESKSARVIRK
     CSSVLNRFLK GIEALQREGK QAPDWNRVDL SEVLKLMEDL IDYFAQPDED DFEASQNRLS
     ALRSRQDLFQ EEGVLNMILD TIDKFSQMEA MPDFAGLLND DTQMMWEEIS TYLYLLVAAM
     IKGNHYNCAQ FASAQRLQWL FGRLSNPQSA EGILDVLYCV LTESPEALNM INESHIKSVI
     SLLEKVGRDP KVLDVLSSLC EGNGMAVRSS QNTITQHLLP GKDLLLQTKM RDHVSSMTPN
     IFVGVVEGSS QFRRWYYEAE VEHIEQMTKT EPYLRIGWAN SMGYKPFPGS GDGWGCIGVG
     DDYYSYGFDG RCIYCANKKH VISTRTLQKG DIVGCLLDLN IPKIRFTING QETTGLFKNF
     NIDGFFFPVM SLSAKVSCRF LFGGTEGRLR FGPPSGFSAL IEAAANQLEI GECVSFGDIG
     KNVYTGPSIL RENTEPFVPK LVDISSVVLP HFAMDIHEKL AENLHELWSM RKIELGWTYG
     EVQVRDEETR RHPCLTSFHQ LPSNEKTYNI NLAIDTMKTI EALRYHMILE EPPVRLRPVR
     LPQNYQQSNG FKPQPLDSHE IVLHDNMFPL IDALAKNTHN VWAREKIRRG WTFGLNEFVN
     ATQKRSPHLV PYEVVDQRIK EANRESATEF IKTLQLFGIF LESPVLEHDE AAEKELQATK
     AFSRTYRAEA LYAVSSGKWY FEFEVLTSGF MKVGWMDVSA QPTVDIGIDD RSYGFDGYLA
     RKWHQGPVTY GREWKIGDIV GAFLDLSDRT ISFSLNGELL LDPSGSEMAF DNITVTDGFV
     PAMTFSVGQK ARLNFGQDSN SLKYFTTCGL QEGYEPFCVN MYRQMPMWYA KRLPQFEDIG
     LNSTIEVSRI LPTASSPPCL KITQKVIDTG DMAAQEKTKM EYIRLSLPVK CNNVLQPTKD
     KESIMRSLQE IEKHLSEEAA HPISTTIVHP AIPREFSDDI KASKRSFGKS LLSAFKHSTE
     EDESSARSKP TSFDSDHHLA PEPSPIRMSG SMLELSNGDD HREGRHKQRG LMAKFHQKKR
     EETSTDSKRT TGTLPDGQIA GADAISAEEI LVSSPSKDEQ DMPMPRSGPG RARRFLTSRK
     WKKQKNQKVL QHRRPSIAAL EQSAVAEGNI LFDDVRPMTE LSDKIDEFYY AIRIFPGQDP
     ANVWVGWVTP KYHFYAERFV SGEAVRRCKF QETNKNVNER ESIEYRNCYM MNAAELLQSV
     PDAGNTKVSG LLIGCIIDTS IGELSFIASK QDTGFRFKLE PGAILYPAAF VAPTSAEILQ
     FELGRIKYTF PLSSAMSKSS HKSLLPFCPP RLTVEKLNPV HWARVPNECL RTTALKLSDF
     RGIIFEQIRH SWSVLCDDPV RIMSIYVPEK DTSYDILEMI EHNDFLTFHR QTLNLYCKLA
     AHGNQKVAHI LCSHVDEDQI MYAVMSHYLS GPLRQGFHDF LIAVHLRTYV DARQSTAREY
     VIPLKQNHEI ENVFHPGSEN RFPQILGPTV SIRPVIACSE VRSDFGTDEE AKLQPPAFNF
     DALKAHVMSA LSSAIEHAVI SCRDLIGGNC LNHFEPLFKL FNSLLVIGMF DDDDIKDVLK
     LIHPIAFDEN YVPGLKQKGL TEIELEEGVK IQLTIILESI CDIQLRHRVE SLVSFAAGFV
     GDLQQDQFAR YMSIKQTDMT SAEAAKRTKE FRCPPREQMF RLVKCKAVSD DSVGIMLDDD
     TEYDQCPMDE TLQQQLRDFC SLLVGKVGCA KDDKSDELSN LVVLDEANSW VDQLAQLVIR
     VPPPLTGEEN DMNHNGTENF RHMICTMLKS WATSSLIESN DLIRKMFSLL LRQYTGVAEM
     MKALSQTYVL HERNIEDVQD FIENLVQVRE LLSVQFESAE ETVLKRGLWK LMNNRIFFQH
     PDLMRLLTVH ENVMSIMMNV LTAQQGAANH TEPAEHVENT EEIANAKESK DASEMVVACS
     RFLCYFCRTS RHNQKAMFEH LSFLLDNATM LLARPSLRAL ALREEELDKV TVYLSRCGLQ
     PNSELVAKGY PDIGWDPVEG ERYIDFLRFC VWINGESVEE NANLVIRLLI RRPECLGVAL
     KGEGQGLFSA FKEAITLSED IRALEEEKNR AIIHSALLKE QPNYPNKETE GEDYIDLGAA
     TLDFYSSLVD LLAKCAPDKI NIQAGKGDCL RARAILRSLI SLDDLGQILA LRFTIPNLIA
     SVAIDDVGPL PGLLPNHKQS VLLFLDRVYG IDSQEMLFHF LEKSFLPDLR AATMMDSPTS
     VENDTALALN RYLCNAVLPL LTSHSHYFAD AEHHAALLDT TLHTVYSMNR LLSLTKNQRD
     AVSDFLVAIT RELPPAMMVK LMRKVISDIQ EMDENLLVPL RILTLHYERC TKYYGLGNVY
     GMASETEKRL SMLLFYAIFD SLGSRQYDPE LFGKALPCLT AIGSAISPDY TLTTTGDDMD
     KIQKAKDRGV WNPDPVDVSR IVVDDDLKSV ISKFAEHFHD SWASRKIEKG WNYGELYSRQ
     ALTHPRLRRF SLLPDFEKNF YQERCAECLR ALLAWNYSIE LTDYDAADRA VQNNNSSGTS
     TENFNPKPVD LSNMTLEKDM TAIAEKMAEE SHKIWAKKVF ADLSRGGPMP PQLVPWDLLT
     DFERRKDRFR AAEILKFLQY HGYRVWSSSK AEPSTERVKI DSERSSVEKR FAYNLLKKLI
     QYLEQASLKM KTIKPSQELT RQNSFRREGQ DVKFFEKVVL PLMRAYFNAH KNYFLASSSI
     VQTGMASDKE KEMVANLFCR LASLLRIKSH AFGSVAKITV RCLQGLTQAL DLRTLVKINS
     DIVRTGLLTF FNNCADDLFS AVEELQNGGQ YSLLRGQNLK SWVSLEFANQ MIIPVLTTMF
     VHLAINHFGS DLLLDEIQAA CYKILDSAYL MNSLAATASQ RKSIAYEMDK HRPALGQCLA
     AFAGCFPVAF LEDQFNKNNK YSLLAKSQDQ SVQVQEMLQN LLAHIPQMDK LLTDVEQVVQ
     SGAMYRDQPA IYDVDLPLIC SYLTYWWQLG PDSNNRSSAP VTDVSSEYIN RIFRALLQMI
     HNHIGVENAS WLCRINFFSV QIIPYVSFDA VKDYILPVAE RLRRLAEKAY REEEHTRTHP
     DDADEGSVAE DNAHLVRDVY AYFPILMKYT DLHRAQWLKS PSWETDGIYE NVAVIFKIWS
     LSQHFKREEL NFMAQYEDES VAGGTGEMKT GKAAIAERKK KRREGQIRKD KHASSIVIAC
     LKRLLPVGLN VFGGRELDIV QQAKEKFLAK EPEDKIRELV RSLLDIPAKT DPTDKNAWQL
     NLYRKIGKSE MRNKDVMTLD GIVEKITSMG QVVAILHVTE HPQGSMDNAW KTMISSQRKR
     AVVACFRMIP LYGIPRHRAI NFFLPAFNKL WLEDEDVGQD ALIKELTMEN GHQEQVHIKT
     GDDEATNDEK DEKSQAPPDP LRQLIQCFQR AATSEQSQTV SIANDSLFVN FAQVMSKSIH
     IEDEDEGDDE GELDQAQKEE ISQALRAEQA VLADRGAAIM CLMYLSASNG EPSDMVAEAL
     QLGIHLLNGG NSKIQEMLID YLQLKKDVRF FTSLAGLMNK CSVLNLEMYE RQIKAEGLGM
     GAGLAAGANQ NLNDSEFTCS LFRFLQLTCE GHNLEFQNYL RAQPGHTTSV NLINCTVDYL
     LRLQESVMDF YWHYSSKDVI DESGKEYFLR AIHVCSQVFN TLTESIQGPC TGNQMTLANS
     RLWDAINGFF FLFAHMMEKL YKNSTQLELL REFLNLQKDM IVLMLSMLEG NVLNGSIGKQ
     MVDALVESEQ NVEMILKFSD MFLKLKDLTT SQAFQDFDTN RDGWISPKEF QRAMESQKMY
     SVEEITYLMM CTDVNNDGKV DYMEFTERFH NPARDIGFNV AVLLTNLKEH ITSDPRLEKI
     IKQASSLLEY FDPYLGRIEI MGSSKKVEKI YFEIQESWLE QWSKQQIRDS KNSFLFNVLQ
     DDGGDQGKLE AFINFCEDTI FEMQHAAEIS AGDMADSKIE RAKKQRDYFL QQTSAGVQIS
     ETFKTGFNYG INAANALKPA NVKKIFNRAN ATVRSMTWTQ LIIAIITLLA KISMKAAMFI
     YLIICTFIRF GYYLMTPDRD EMEVEQAALP MPESASMPYS SPVLPSVQQY QRFSNYDVFG
     VRLPSAQPSA ASQGQSKTEI TNGPIPVPQS DTVLKPSATV QQHPSLYETQ SISGTAAQYN
     QVASPTISEY GTADYYEPKI AEQIPPRSRG SLLNMLARNF KTIEKTTLYL AFFINVILLF
     HRIKISDSGA SEGLEGEGDG DEEMESVYIS GVILPYTSYE VTGWMLAQLL YWISVLHAIA
     SFALLVSFYQ LKIPLITFKR EKEVARRLMF DGCWLTEDDD EERSLVNTVF WYIDRIVISS
     KSFPMKYWDK FVRRKTRHKF RDQIDEDTLI TVLGEDKPAT DTAFDYRYAC WLWLGVILTN
     GQFLYRVHYL LCSALGVFVS PFFYAFHLID VVLSFPMLKA ILQSVTHNLQ QLILTIMMTL
     VVVYLYTVLA FNFFRKFYVQ EGEGEEPPDR KCHNMLTCFI YHFYAGVRAG GGIGDELESP
     YGDDLEYWRM LYDISFFFFV IIILLAIMQG LIIDAFGELR DQQESATEKL ESSCFICDIG
     KETFDRLPRG FEIHTSKEHN FANYLFFLQH LVNKDETEYT GQETYVREKY DNRDWEFFPV
     GECFMKQYED QLLQS
//
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