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Database: UniProt
Entry: A0A158QG84_HYMDI
LinkDB: A0A158QG84_HYMDI
Original site: A0A158QG84_HYMDI 
ID   A0A158QG84_HYMDI        Unreviewed;      2903 AA.
AC   A0A158QG84;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   07-JUN-2017, entry version 10.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|WBParaSite:HDID_0001015901-mRNA-1};
OS   Hymenolepis diminuta (Rat tapeworm).
OC   Eukaryota; Metazoa; Platyhelminthes; Cestoda; Eucestoda;
OC   Cyclophyllidea; Hymenolepididae; Hymenolepis.
OX   NCBI_TaxID=6216 {ECO:0000313|WBParaSite:HDID_0001015901-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000046397, ECO:0000313|WBParaSite:HDID_0001015901-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:HDID_0001015901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
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DR   WBParaSite; HDID_0001015901-mRNA-1; HDID_0001015901-mRNA-1; HDID_0001015901.
DR   Proteomes; UP000046397; Genome Assembly.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF02026; RyR; 2.
DR   SMART; SM00054; EFh; 2.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
PE   4: Predicted;
KW   Calcium {ECO:0000256|PROSITE-ProRule:PRU00448};
KW   Complete proteome {ECO:0000313|Proteomes:UP000046397};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000046397};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2220   2239       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2422   2441       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2503   2525       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2642   2665       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2703   2724       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2784   2805       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN     1979   2013       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   DOMAIN     2014   2049       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   CA_BIND    1992   2003       {ECO:0000256|PROSITE-ProRule:PRU00448}.
FT   CA_BIND    2027   2038       {ECO:0000256|PROSITE-ProRule:PRU00448}.
SQ   SEQUENCE   2903 AA;  324929 MW;  C0D22E0E1DB607FB CRC64;
     MAIDAEAQGL NPENEDMGWR TVLMDYEDCN LFAPLPYNFS NLPPEEDEDY VDLGAAILTF
     YSVLVDLLGR CAPELDTSKS ESVRGRAILQ SLVSMQDLEG VLSLRFILPP PKLEMQLNAE
     GLEQWVDKSP MPPGLLPEHK AAVVLFMERV YGLSDPDTFV RLLENAFLPD MRAVTLLDSA
     QRGVTASDMT LALNRYICGS VLPLLTRYAH FLAVNEVTAG LLESTLHTAY RLATCRSITN
     NQRDVVSDFL VALVEHIQPF SMTSLIRKIA KNMRTVGRES VVSLRVLTTF YQRFGAYYSS
     EGWTAEYASS GPDTSGVAGG VASTGSASKP TSGQSASASG AARDLSDTTF VRPTAAGTTA
     TATEEERNLT AELFSLIFNN LSGRRYDAEL YVYALPCLTA IGCALPPDYC SSHWDAQSRI
     GEYDLIGADA SVHPGGPDSA VDLRGSNKQH ESFRPMPLVT STIKLPAALS ILVDQFAKHC
     HDTWAQELVD QGYVYGLTLD ETRRTHPNIR PYHSLSQRDQ MRYIQPVTET LRAMLALGWT
     IDPSGVCHED DGTGLGYHRR QFGHNQAEGP QTYIPAPKDL HGVNVTRELI DLAERLADNA
     HQIWAKQKME ELEEIGGGVH QLLVPYDILT DRERKRYRRL THELIRYLQY WGYRLSCKPT
     NQQQDNTAIP GTTATPNAVS ANMAKQIAGE RGEGACRPFW DIYAFKLFLL GHPSSRFAYG
     LLSKLLDYVE GAMSTVREDK PSRMFSRYQN LTQTSEDMKL LVKVVLPLLE RYFYTRKSYF
     IDPYSGASIE EKKMATMLFT KLFTLLRLKT RCFGADVNVT VSCLKCLIEC LDIKAIVKIS
     YAEDFVRVRL MPFFAFCADD LNLLIRNLNS GRYSHTKARF SHFLNSHCYL SGTIRRGACS
     IDYVHMILLP TLKTMFEHIS KTGVGEDLLL GHLQVTSYRI LNALYVLGTT SRKHANRHEL
     MEELNRHRPM LGECLAALTT CFPVAFLEPE LSAHNPRSIA YNTEEADYSF EARDLLQKIG
     KTLPFLHEII DDIVRLAESG SNCVDEPHLI EVTLPMLCSY LPVWWRKNLA QRRYARRHPG
     SKAASFFPDN EEFLAALDVM EGEEPEAVAG TGGADGEGGE GGGENDDDDE EKGWGATTGP
     ITTVTADLMN RVLGSVLQLI QNNIDNSNAP WMTRIASNES DKESELTAAC ELLVRNMFAL
     YPLLITFVDR YRTEWLKQPT METDRLFNAV ANLFLIWNGS PNFKREEETF VGIHELDTLA
     LIMPSSERST VSADVGPRSQ ATKSGKGQKK GFTSLMVASI KRLLPIGLCV LGGRQQELVQ
     RAKRMFLKHE VEADIADYLR YALDKDDDSE TKVYRWQKLL YQKIDRTIVL TGCHEALGIP
     TKEEVINRVM TLAKVMHALY LVGHVAPTTL NRGAWKKLVS TQRKRAVMAC FRMQPFYALP
     RHRAINFFLM AYHDGWLSYE QSLGVQLIEE ITGAPFEENA VLNASNAASV APIAGMLPAS
     PSDNAIGASP DSSGGQGDSS SGGASGETEA ASNVARTIIE ASIYSESSDE DNVSLNAAEG
     IIATTSAASA STNEQASGGE NAVGHAEGAG HPVFATDYCA TPDPLRQLLT ALCRTAMEQA
     PDDPLYLAFA RIMAKSCSGT DDDDENSGSG GGGSGEDEGE NGEEEEGPSS QEQEEQKQRL
     LFEQNRLSDR GAAEMVLLQI AASKGEATPV AMASVELGIA ILLEGNVSVQ NRMLAYLAEK
     RLTGFFTSLA GLMQNCSVLD LDTFERCRKA EGLAVGLSDM EGITNLYDAD FTCKIFRLLQ
     LMCEGHNSAF QDYLRTQSSN TTSVNLIICT VDYLLRLQES IMDFYWHFSN KPIIDESGRT
     NFLKAIKIGK QLFRTLTEYI QGPCQGNQHA LANSRLWDAI SGFFYLFAHM QDKLSKDPER
     LDLLHEFLNL QTEMMIMLLS MLEGNVVNGS IGRQMVDTLA ESSANVELTL TFFDIFLRMK
     EITNSDAFLA FDVNKDGWIS HREFRTALEQ QKSLTEDEIN YIMSCVDANS DGKIDFQEFT
     ERFYNPARDI GFNVALLLTN LSEHIPGDPR LERLLQKAKG MLEMFDPLLG RIEITNKEGR
     IERVYFEVRQ ENIDQWEKPH IKESKRTFLH SVVGESGDKE KLECFVNFAE DTIFEMQHAQ
     SISGDDENLQ ISRVVAVRNL LEATRLSSVF TFLGTLVSFL SPHHLWSSWT KLRQMSVADV
     IADILGLIIG LMIGVVRLLK GVLKITGRFI VAMASDPTAQ PPPAQQSMSR WQNAGGTRGM
     SNSVRFGGGK VDGNLMANGD SKPPDTVVTN EEAQKSTDFA NILQEKECWL LSEEEQLLLE
     RVDSSKVEAF TRSSNRKSAT AGGSRLSAAG RKKETGTSEG KRKLSSHSVT IEEGSTVTEQ
     KSIPTSTFLI SIFARNFYRF KLCALVLAFI INFLLLCYKI EKRPLGGEDI EEAELGTTFV
     TTISDTVSNI ADSLQNSEVD IGSEGEEEEF ITLAESASYL GPLLKILAIA HSILSMSMLV
     AYYFLKVPLI IFKREKEISR MLEFEGVWIA EQPSDDGLRA QWDKLVLSTP SFPHMYWDKF
     VKKKVLKKYR EQYDQKQVMR LLGMKPGSPN NCSSPSKERP EETPSSWFYP TWLQEMDLQY
     LLWKWGVIFT DNSFLYLVVY FIVSLLGNKN YFFFSCHLLD VAISFKTLAT IVQSVTHNGK
     QLVLTVMLTS IVIYLYTVIA FNFFRKFYAK EEDGEKEYKC NDMLTCFIFH LHMGLRAGGG
     IGDEIEAPDG DAHEALRIIF DMTFFFIVII ILLAIIQGFI IDAFGDLRDQ LEQVREDLES
     KCFICGIGKE YFDATPHGFD RHVEREHNFA NYMYFLMHII NKPDTEFTGQ ETFVWELYQQ
     RCLDFFPIGN CFRKQYEEEL QAK
//
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