ID A0A158R1I7_NIPBR Unreviewed; 289 AA.
AC A0A158R1I7;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=TIMELESS-interacting protein {ECO:0000256|RuleBase:RU366049};
GN ORFNames=NBR_LOCUS13884 {ECO:0000313|EMBL:VDL77473.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0001388301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0001388301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL77473.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays an important role in the control of DNA replication and
CC the maintenance of replication fork stability.
CC {ECO:0000256|RuleBase:RU366049}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU366049}.
CC -!- SIMILARITY: Belongs to the CSM3 family. {ECO:0000256|ARBA:ARBA00006075,
CC ECO:0000256|RuleBase:RU366049}.
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DR EMBL; UYSL01021174; VDL77473.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A158R1I7; -.
DR STRING; 27835.A0A158R1I7; -.
DR WBParaSite; NBR_0001388301-mRNA-1; NBR_0001388301-mRNA-1; NBR_0001388301.
DR OMA; MKKYAYW; -.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR GO; GO:0000076; P:DNA replication checkpoint signaling; IEA:UniProtKB-UniRule.
DR GO; GO:0031297; P:replication fork processing; IEA:UniProtKB-UniRule.
DR InterPro; IPR012923; Csm3.
DR InterPro; IPR040038; TIPIN/Csm3/Swi3.
DR PANTHER; PTHR13220; TIMELESS INTERACTING-RELATED; 1.
DR PANTHER; PTHR13220:SF11; TIMELESS-INTERACTING PROTEIN; 1.
DR Pfam; PF07962; Swi3; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|RuleBase:RU366049};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU366049};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366049};
KW Reference proteome {ECO:0000313|Proteomes:UP000271162}.
FT DOMAIN 128..209
FT /note="Chromosome segregation in meiosis protein 3"
FT /evidence="ECO:0000259|Pfam:PF07962"
FT REGION 222..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 289 AA; 33654 MW; 77E3DBC827C12667 CRC64;
METKCEKART NMIVKVMHFD HIVLTSMRGP TAGLHKVREN TVSESCIQGD DEACLWQNVQ
LMRRHVLRRP EPEPPMDEFD EINDFFGDSL SDNGADENDE SSNVLNNLLE KENREVAKKR
TVTRPQPKLN EATLTGPKGI EALRNSFSNY KPDLKKDPYE NLAVMLKKYE HWAHVMFPKL
KFEDVVSRCE TLGDKRPVKV YMMKSRLGMK LTDEDFAPVR RKKGDEIIET ENNEDDAGRI
RERDSSDDEE NYYDPLESAH SSAEEEERRR REEAELAMVN EVMEDFDMY
//
