ID A0A158R384_NIPBR Unreviewed; 475 AA.
AC A0A158R384;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=ATP-dependent RNA helicase DDX1 (inferred by orthology to a human protein) {ECO:0000313|WBParaSite:NBR_0001772801-mRNA-1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0001772801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0001772801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
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DR AlphaFoldDB; A0A158R384; -.
DR WBParaSite; NBR_0001772801-mRNA-1; NBR_0001772801-mRNA-1; NBR_0001772801.
DR OMA; WSTDKAT; -.
DR Proteomes; UP000038043; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12873; SPRY_DDX1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022722};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 42..219
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT DOMAIN 218..380
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
SQ SEQUENCE 475 AA; 52007 MW; 3ED0848D786AD742 CRC64;
LPTPIQCDAI PAILGGGDVL IAAETGSGKT GAFSLPVVQI VWERRKDQMN PKSGGSSGGV
GWRLNLGDRA MGLSLSQDGL SCESRVPKAW FGSRCMGGVH TRGKYYYEAK ITRDGLCRIG
WSTLKASLDL GTDQESFGFG GTGMKSTQRK FEKYGESFTT GDVLGCYLDL DNGRWSKNGK
EFEVAYRLDG KFSSPHCAMH PAVLVQNSSL QLNFGATPFA FPPKEGIIAV CEAPANLIEW
RGLEAEEQKN DSSAAPVCIV LEPTKELIDQ THDNLVKFSK NVSDPKLRCV SLAAGLSMAQ
VLNELDKGVD IVTGGVGRVL DMIETRKLST TGLNFVVIDE ADQILSQWKP QLERLLMINV
TLPDEAPQYV HRIGRVGRAE RMGLSISLVS THNEKVWYHK CGNRSCRNTE DLSKGGCTIW
YNEPKLLADI EEHLGQTISV VDSAFQIPVD EFDGKIVYGA KRTNGKNSNL FIYFL
//
