ID A0A158R8E5_TAEAS Unreviewed; 934 AA.
AC A0A158R8E5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000313|WBParaSite:TASK_0000529001-mRNA-1};
GN ORFNames=TASK_LOCUS5291 {ECO:0000313|EMBL:VDK34828.1};
OS Taenia asiatica (Asian tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Taenia.
OX NCBI_TaxID=60517 {ECO:0000313|Proteomes:UP000046400, ECO:0000313|WBParaSite:TASK_0000529001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TASK_0000529001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDK34828.1, ECO:0000313|Proteomes:UP000282613}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the alpha-actinin family.
CC {ECO:0000256|ARBA:ARBA00010255}.
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DR EMBL; UYRS01018405; VDK34828.1; -; Genomic_DNA.
DR STRING; 60517.A0A158R8E5; -.
DR WBParaSite; TASK_0000529001-mRNA-1; TASK_0000529001-mRNA-1; TASK_0000529001.
DR Proteomes; UP000046400; Unplaced.
DR Proteomes; UP000282613; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd21214; CH_ACTN_rpt1; 1.
DR CDD; cd00176; SPEC; 2.
DR Gene3D; 1.20.58.60; -; 4.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR014837; EF-hand_Ca_insen.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR11915:SF422; PH_9 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF08726; EFhand_Ca_insen; 1.
DR Pfam; PF00435; Spectrin; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00054; EFh; 2.
DR SMART; SM01184; efhand_Ca_insen; 1.
DR SMART; SM00150; SPEC; 3.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000282613};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 44..148
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 157..263
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 780..815
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 830..865
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 589..665
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 934 AA; 107607 MW; F32A48DDC88E4119 CRC64;
MSGGSRKVET HQTKSIFEFE GYPNDDDDEE VPERETAIDP IWEKQQKKTF TAWCNLHLKK
KNVEISVIEE DFRNGLNLLI LLEAISGEQL PPPERGKLRV HRILNVNKAL DFIQKKGVKL
VGIAAEEIVD GNVKMTLGMI WTIILRFAIQ DIQIENCSAN EGLLLWCQRS TEPYPEVDVK
NFNTSFKDGK AFCAIINRYR PDLLDFNDVA KAPARDALTK AFDVAEESLS IPKMLDVDDM
LESVKPDDRS VITYVSCFFH LFSEAGKTSA AATRIKKAVE ISQMSDQLRD SYNRLFTDLK
EWIIEKKAYF DHREPILNLE DVNRSIEGLR QYQTEEKPAK IEEKSHLETT FRTLQTRLRL
NNRPPYLPSD GMLIADILIL WKELEICEKN YEEWLMGERK RTTTLAYWLS RFEVRCKTFE
AWAAGKSDYL QSSDHTTCTV AEVRPMLKKH EAFVSDLMAQ QDRVERIDSI AKEIRNLGYT
DMPSIDNRCA QIKNSWDSLK ALSDKRHLNL SEAQSVLEKV DAKHLEIAKL SAPFHNWMQQ
AEEDLRDKFI AQSIADVETC VCDQGQRNQA ISRSYFYNLR TFQKLINTHG ECEKSLKEKE
KEYEKIKDLE VEIDCLCKQI NRNSIANPYT NVTTSMLHEQ WKMLQELADQ RRKELEEEKK
RQLASDQVRK LFIQLATELN GWLEQTQGRL NNVGLGEASL EEQVELLNNL DVELEAQRPK
LGELEDCHQQ LQDAYEDLDL PVSMATLRSV WNQLSTGLKY TRNEIENQIL TRDSKGLSKT
QLDDLRRCFN HFDKDHTGRL ECPEFKACLV SIGHSIVAED KKQRKTSVDT SDEDILKLMK
QLDPNSNGSI AFDVFVDYMT RELTDLDTSD QLLQSFRTIS GEKGYLTEAD LRRELPPEQA
EYILSKLQPL SGGPAGDTGA LDFEHYVLTI YGTK
//
