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Database: UniProt
Entry: A0A158R8I4_TAEAS
LinkDB: A0A158R8I4_TAEAS
Original site: A0A158R8I4_TAEAS 
ID   A0A158R8I4_TAEAS        Unreviewed;       888 AA.
AC   A0A158R8I4;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   15-FEB-2017, entry version 5.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
OS   Taenia asiatica (Asian tapeworm).
OC   Eukaryota; Metazoa; Platyhelminthes; Cestoda; Eucestoda;
OC   Cyclophyllidea; Taeniidae; Taenia.
OX   NCBI_TaxID=60517 {ECO:0000313|Proteomes:UP000046400, ECO:0000313|WBParaSite:TASK_0000551901-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000046400, ECO:0000313|WBParaSite:TASK_0000551901-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:TASK_0000551901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   WBParaSite; TASK_0000551901-mRNA-1; TASK_0000551901-mRNA-1; TASK_0000551901.
DR   Proteomes; UP000046400; Genome Assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000046400};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000046400};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    434    459       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    480    497       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    575    596       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    608    628       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    671    690       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    820    845       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED       94    121       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   888 AA;  101475 MW;  EC0BA5341FC26013 CRC64;
     MGSIFRSEEM QLSQLILHTD SAYMCIAQLG ELGVVQIRDT TPEVNAFQRK FVDEVRRCDE
     MERKLRYIEN ELQKDDFPIF EPDEVPEAPP PREMLDLESN LDKLENELRE VNFSLEQMKK
     SFMELTELKM VLRRAQIFFE EGSYEVNVNL GGGDEMLVEV SESREPRDLR SGYIEMVPQS
     DDFDVGFRQG HATSTTYSSH HVDFVAGVII RERTVPFERM LWRACRGNVF LRYADLESIE
     DPATGELLDK CMFIVFFQGP QLRSRVENIC DGFHATLYAC PDTQEKRQAM LLDVTSRRED
     LQVVLNRTSE HRARVLETAA QSLREWFYKV YKMKSVYHAL NLFNLDVTTK CMVGECWSAV
     SDLDAVQIAL RRGMELSNSS LQPILNRLHT TEKPPTFHRV NKFTSVFQNI VDAYGVAKYR
     EVNPALFTVI TFPFLFAVMF GDAGHGAIMF LVALFLVLWE KKFIAKKIKG EFWDTLFGGR
     YIILLMGAFS IYTGMIYNDI FSKSANIFGS SWFPLFDNRT LERSEALQLN PDAHIGSEPA
     STGMFAGFPY AFGLDPVWQV SHNMIMFTNS LKMKMSIILG VLHMLFGILL GAFNYRFFKN
     SLSIYCDLIP EVLFMLSIFG YLVFMIFYKW VVFYSKDAST APSLLISLIN MMKFDYGKKD
     DTQFLYNGQP IVQSILVVIA LLCVPWMLLA KPLILYRRHK VRNTLGAIRA TGFGELGNTG
     DPEAGTGTND YVPFRNEASP KFEAPSDPEV PHSEGGHGDS EEFVFGEVMV YQAIHTIEFC
     LGCISNTASY LRLWALSLAH AQLSEVLWEM VMMNALKVNG YYGAIILFFV FAVWASLTVG
     ILVLMEGLSA FLHALRLHWV EFQNKFYEGS GYLFEPFSFA NIEKLSVE
//
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