ID A0A160FAL4_9BACI Unreviewed; 763 AA.
AC A0A160FAL4;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:ANB63919.1};
GN ORFNames=GFC29_1783 {ECO:0000313|EMBL:ANB63919.1};
OS Anoxybacillus sp. B7M1.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Anoxybacillus.
OX NCBI_TaxID=1490057 {ECO:0000313|EMBL:ANB63919.1, ECO:0000313|Proteomes:UP000076753};
RN [1] {ECO:0000313|EMBL:ANB63919.1, ECO:0000313|Proteomes:UP000076753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=b7m1 {ECO:0000313|Proteomes:UP000076753};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP015436; ANB63919.1; -; Genomic_DNA.
DR RefSeq; WP_044744585.1; NZ_CP015436.1.
DR AlphaFoldDB; A0A160FAL4; -.
DR KEGG; anl:GFC29_1783; -.
DR PATRIC; fig|1490057.3.peg.2028; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000076753; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000076753};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 473..490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 503..716
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 763 AA; 87409 MW; 8575FE5C7C69FF80 CRC64;
MRGNGVYVAI AAIGGITAGY QRLHGLHFVM AVYLLFLLRY KRDLLPACLL AAALFYLYMI
WTETHNQTVL PKNKTHFSLR LIEPPVIDGD QLKVKGRTKE KEKVQLLYKI NRERDKKELF
QLRMGMVCRF EGRLEAPEPA RNFFAFDYRK YLRSQQIHWI VKPSSFSVAA CKQTRLHPVE
VLRSIREKGM DEINEHFPPA VIGIVQALIF GEREEMDEAL LEGYQKLGLV HLLAISGSHV
TLLVSGCFYL FIRFITREAA ALILILLLPL YMILTGASPS VVRASVMAMM LLWSRYRKFN
IPLSDILSLT CIVMLLIQPY DLFQPGFQLS FIVSFALILS MDWIEQYRSS MMRLFAATLV
AQISSLPFLL YHFFEFSLLS IPLNMIFVPF YSFIILPLSI IALVAHYVVE PLSLPFIYLL
EHVLDFANRF VQFFAFDRSL AFVLGRPSML LLLCYGMAIV WAFTQMEQKK YRAFGYVVIV
IAFHAAFPYM NRYGEVVFLD VGQGDCIYIE LPYRKGVYLI DTGGTVLLPK QSWQKRRSEW
RVGEKLVVPF LKAKGIRQLD QLIITHGDAD HMGAAPEVIR SIRVKELVIG NESRAYSPWQ
TALMAGMKDR KMKIRKVEKG DDWKVGEASF YVLNPSRTAL PSNDNDRSVV LYAKLGGLSW
LFTGDLEAEG EGRLIRDFPH LQVDVLKVGH HGSATSTSEP FLKMIKPQIA IISVGKNNRY
HHPHHDVIAR LKKHGVRILR TDEHGAIRYR YTKKAGTFTF MLP
//
