ID   A0A161PVD4_9FIRM        Unreviewed;       475 AA.
AC   A0A161PVD4;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Vancomycin B-type resistance protein VanW {ECO:0000313|EMBL:KYO64454.1};
GN   Name=vanW {ECO:0000313|EMBL:KYO64454.1};
GN   ORFNames=ATZ99_18820 {ECO:0000313|EMBL:KYO64454.1};
OS   Thermovenabulum gondwanense.
OC   Bacteria; Bacillota; Clostridia; Thermosediminibacterales;
OC   Thermosediminibacteraceae; Thermovenabulum.
OX   NCBI_TaxID=520767 {ECO:0000313|EMBL:KYO64454.1, ECO:0000313|Proteomes:UP000075737};
RN   [1] {ECO:0000313|EMBL:KYO64454.1, ECO:0000313|Proteomes:UP000075737}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R270 {ECO:0000313|EMBL:KYO64454.1,
RC   ECO:0000313|Proteomes:UP000075737};
RA   Patel B.K.;
RT   "Draft genome of Thermovenabulum gondwanense isolated from a red
RT   thermophilic microbial mat colonisisng an outflow channel of a bore well.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KYO64454.1}.
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DR   EMBL; LOHZ01000042; KYO64454.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A161PVD4; -.
DR   STRING; 520767.ATZ99_18820; -.
DR   PATRIC; fig|520767.4.peg.2008; -.
DR   Proteomes; UP000075737; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR011098; G5_dom.
DR   InterPro; IPR007391; Vancomycin_resist_VanW.
DR   InterPro; IPR022029; YoaR-like_PG-bd.
DR   PANTHER; PTHR35788; EXPORTED PROTEIN-RELATED; 1.
DR   PANTHER; PTHR35788:SF1; EXPORTED PROTEIN-RELATED; 1.
DR   Pfam; PF12229; PG_binding_4; 1.
DR   Pfam; PF04294; VanW; 1.
DR   SMART; SM01208; G5; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          370..445
FT                   /note="G5"
FT                   /evidence="ECO:0000259|SMART:SM01208"
SQ   SEQUENCE   475 AA;  54931 MW;  E7918AC064AA9C92 CRC64;
     MEGGFMRKNF FIILLLCIIL VFFVIILIFI YQQNNDILPY NVRIGPIDVS KLRKEDASLK
     IQSYIEEKND QKIIFRYNNK KYEITVGELI IFNPEKSIKE ALLIKKEEFF LKSFYLDKFN
     KRKVTIIPLN YAINEQNLQS IITKIEKEIC TLPQNARFTF RQNKLQIIDE KEGTEIDKEL
     LKTMISNKIF DDEIIIDLPL KKIKPFYTKE KLKNMNIKYE IASFSTRFNL NQKDRINNIK
     LASEILNGII IAPTEVFSFN ETVGERTKEK GYTDAPIYFN NEVIQGTGGG VCQISTTLYN
     LVLLADLEVI ERHHHSMPVG YVPPGRDATV SYGILDLKFK NSTGGYLVLS TEIIGNNLVM
     KFFSNEKFNK KIDIISEIVN TFPPGKIQKI DNNLELGKTR IEEGRPGCKV KVWKIINYQD
     RIEKKLVSID TYKPLNTIEY VGKKPISSLN QYIDKEDPSV ENNTNDLLDI NAVNQ
//