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Database: UniProt
Entry: A0A161U1W7_9MICO
LinkDB: A0A161U1W7_9MICO
Original site: A0A161U1W7_9MICO 
ID   A0A161U1W7_9MICO        Unreviewed;       472 AA.
AC   A0A161U1W7;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   25-OCT-2017, entry version 13.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:KZE89741.1};
GN   ORFNames=AVP41_02543 {ECO:0000313|EMBL:KZE89741.1};
OS   Microbacterium sp. TNHR37B.
OC   Bacteria; Actinobacteria; Micrococcales; Microbacteriaceae;
OC   Microbacterium.
OX   NCBI_TaxID=1775956 {ECO:0000313|EMBL:KZE89741.1, ECO:0000313|Proteomes:UP000076535};
RN   [1] {ECO:0000313|EMBL:KZE89741.1, ECO:0000313|Proteomes:UP000076535}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TNHR37B {ECO:0000313|EMBL:KZE89741.1,
RC   ECO:0000313|Proteomes:UP000076535};
RA   Adelskov J., Patel B.K.;
RT   "Draft Genome Sequence of Microbacterium sp. TNHR37B isolated from the
RT   Great Artesian Basin of Australia.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KZE89741.1}.
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DR   EMBL; LQGV01000003; KZE89741.1; -; Genomic_DNA.
DR   RefSeq; WP_067165950.1; NZ_LQGV01000003.1.
DR   EnsemblBacteria; KZE89741; KZE89741; AVP41_02543.
DR   PATRIC; fig|1775956.3.peg.2540; -.
DR   Proteomes; UP000076535; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000076535};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076535}.
FT   DOMAIN      165    293       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      377    446       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     173    180       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   472 AA;  52531 MW;  CB66036D36D6C9EA CRC64;
     MTPHDLPDVP VWTAVLDALA DDERVTPQLQ GFLSLAVAQG VMSGTLYLDV PNDLTAAQLN
     KRLRTPIMEA LARVDAEPAA STFRVVVNPD LADAHLTAPV PVQSTAPTMP VSRPPIEDYT
     EPVAAPSRHD TRLNPKYTFD NFVIGQSNRF AHAAAVAVAE APAKAYNPLF IYGDSGLGKT
     HLLHAIGDYA LSLYTGIRVR YVSSEEFTND FINSIANNRG AAFQARYRDV DILLIDDIQF
     LQGRAETQEA FFHTFNTLHD HDKQVVITSD VPPRHLTGFE DRMRSRFEWG LITDVQAPDL
     ETRIAILRKK AQSERLLVPD DVLEYIATKV SSNIRELEGA LIRVSAFANL NRSTLDISLA
     QTVLRDIVDQ DDANVISPTD IITATAQYFR LSVDDLYGSS RSQSVATARQ IAMYLCRERT
     NLSLPKIGQL FGNRDHTTVM YAYKKISELM KERRSIYNQV SEITTQLGRA GR
//
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