ID A0A162DB86_9CRUS Unreviewed; 466 AA.
AC A0A162DB86;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Caspase Dronc {ECO:0000313|EMBL:KZS09434.1};
GN ORFNames=APZ42_026239 {ECO:0000313|EMBL:KZS09434.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS09434.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS09434.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS09434.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS09434.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C14A family.
CC {ECO:0000256|ARBA:ARBA00010134, ECO:0000256|RuleBase:RU003971}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS09434.1}.
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DR EMBL; LRGB01002066; KZS09434.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162DB86; -.
DR STRING; 35525.A0A162DB86; -.
DR EnsemblMetazoa; XM_045171337.1; XP_045027272.1; LOC116919288.
DR EnsemblMetazoa; XM_045171338.1; XP_045027273.1; LOC116919288.
DR EnsemblMetazoa; XM_045171339.1; XP_045027274.1; LOC116919288.
DR EnsemblMetazoa; XM_045171340.1; XP_045027275.1; LOC116919288.
DR OrthoDB; 3020101at2759; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0043065; P:positive regulation of apoptotic process; IEA:UniProt.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd01671; CARD; 1.
DR Gene3D; 3.40.50.1460; -; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR029030; Caspase-like_dom_sf.
DR InterPro; IPR033139; Caspase_cys_AS.
DR InterPro; IPR016129; Caspase_his_AS.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR011600; Pept_C14_caspase.
DR InterPro; IPR002138; Pept_C14_p10.
DR InterPro; IPR001309; Pept_C14_p20.
DR InterPro; IPR015917; Pept_C14A.
DR PANTHER; PTHR47901; CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18; 1.
DR PANTHER; PTHR47901:SF8; CASPASE-3; 1.
DR Pfam; PF00656; Peptidase_C14; 1.
DR PIRSF; PIRSF038001; Caspase_ICE; 1.
DR PRINTS; PR00376; IL1BCENZYME.
DR SMART; SM00115; CASc; 1.
DR SUPFAM; SSF52129; Caspase-like; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS01122; CASPASE_CYS; 1.
DR PROSITE; PS01121; CASPASE_HIS; 1.
DR PROSITE; PS50207; CASPASE_P10; 1.
DR PROSITE; PS50208; CASPASE_P20; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT DOMAIN 213..344
FT /note="Caspase family p20"
FT /evidence="ECO:0000259|PROSITE:PS50208"
FT DOMAIN 381..460
FT /note="Caspase family p10"
FT /evidence="ECO:0000259|PROSITE:PS50207"
FT REGION 156..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 466 AA; 53537 MW; A51676C3E6F3A727 CRC64;
MEQCDQDTIL RSLVDLTKLL DLNPRFLSLL QQKYRVFSQQ MVEDILKNET PALELCFMLV
KRGPNAYNNF VGALRETNQL EVLSVLEVTR SNLNQPAYQF IPSRETNAIP IRRRNQSGES
RDISNGDFNL SNVLYSSSSP QCDEYRRRVL QPPNYIEVDP FQPAPRERSS SFRGSPVTDA
LPPDYNLLDI RVTIGDEIKG LGQDIYPNRN IFPRGLALIM NFEKFNGDIV GRRVGSEKDV
IHLDQLLQQL GYKVIIKSDL TWNETNDELE LFTKSEDHTE ADSVVVAVMS HGKSGTHDEG
TLIYTKDCKF FSSEDLLRRF NNLNCPLLKG KPKIFFFQFC RGDNIDIGHR IAPVVFQSGR
TVTDGNPVPT SPTEIERSYG DMLITYSTLP GYVSYREESE GTWFIKALSL TFMRDAHECH
VDRLLQIVDE QIRHWTGTRN GKQTLEIIKR GFNRKFYFNP GLWKIQ
//
