ID A0A162P0I4_9CRUS Unreviewed; 552 AA.
AC A0A162P0I4;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=APZ42_014884 {ECO:0000313|EMBL:KZS18415.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS18415.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS18415.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS18415.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS18415.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS18415.1}.
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DR EMBL; LRGB01000512; KZS18415.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162P0I4; -.
DR STRING; 35525.A0A162P0I4; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06565; GH20_GcnA-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR038901; HEXDC-like.
DR PANTHER; PTHR21040:SF13; BETA-N-ACETYLHEXOSAMINIDASE; 1.
DR PANTHER; PTHR21040; UNCHARACTERIZED; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 116..275
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT REGION 48..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 552 AA; 62968 MW; 55E5BC389366E3EB CRC64;
MAVLVKLCSQ WSAKRFLWLV TIVFVLVTLC WYMKSPLSAE TGQHKFDCSQ TSSSEAANRM
EDGDMETEQT SSYEPLFKSK IVHIDLKGSP PKPTYFSELF PLLAKLGATG ILIEYEDMFP
YTGTSLESTP ALNAYTPSMV SQINQLAKEN HLEVIPLIQT FGHLEFLLKL PQHMHLREVP
DQPQAICPTH NETLPLLFQL LQQVAKLHPE SKRIHIGADE VYFIGRCTAC QDRMNNKLWS
TSDLFIDHVS AVAKFVNGKL GMRPMMWDDE FRSFTEPQLV QSGIGSLVDL VVWNYKPTLE
LDRDIWAKYL NVFDAIWAAS AFKGATGSNQ QITSVRYHVE NHRAWLRLIA EYRDTPYLSK
FKGIMLTGWS RYDHFAVTCE LLPAAFPSLA VDLLLLQYGE NHVHLADQEA VQYLGCTGSF
IFQQSQDTYY PSCNFPGWEV FSVIQNYGQV MEQYAKVLND SVVRGWLTDY NLAKQFSSPT
HLSGIGTELS YLQNSFDALK RESEIAFPAV YDMNTTKEWF ESHVKPMADK VSELLMGIEV
LRSKNVWPRR PI
//
