ID A0A162RPL9_MUCCL Unreviewed; 675 AA.
AC A0A162RPL9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=phosphatidylserine decarboxylase {ECO:0000256|ARBA:ARBA00012243};
DE EC=4.1.1.65 {ECO:0000256|ARBA:ARBA00012243};
DE Flags: Fragment;
GN ORFNames=MUCCIDRAFT_168620 {ECO:0000313|EMBL:OAD07799.1};
OS Mucor lusitanicus CBS 277.49.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=747725 {ECO:0000313|EMBL:OAD07799.1, ECO:0000313|Proteomes:UP000077051};
RN [1] {ECO:0000313|EMBL:OAD07799.1, ECO:0000313|Proteomes:UP000077051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 277.49 {ECO:0000313|EMBL:OAD07799.1,
RC ECO:0000313|Proteomes:UP000077051};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA Mccluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De Vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyruvate; Xref=ChEBI:CHEBI:15361;
CC Evidence={ECO:0000256|ARBA:ARBA00001928};
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis. {ECO:0000256|ARBA:ARBA00024326}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAD07799.1}.
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DR EMBL; AMYB01000001; OAD07799.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162RPL9; -.
DR STRING; 747725.A0A162RPL9; -.
DR VEuPathDB; FungiDB:QYA_168620; -.
DR OrthoDB; 51217at2759; -.
DR UniPathway; UPA00558; -.
DR Proteomes; UP000077051; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR003817; PS_Dcarbxylase.
DR InterPro; IPR033177; PSD-B.
DR NCBIfam; TIGR00163; PS_decarb; 1.
DR PANTHER; PTHR10067; PHOSPHATIDYLSERINE DECARBOXYLASE; 1.
DR PANTHER; PTHR10067:SF17; PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME 2; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF02666; PS_Dcarbxylase; 1.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Pyruvate {ECO:0000256|ARBA:ARBA00023317};
KW Reference proteome {ECO:0000313|Proteomes:UP000077051};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT DOMAIN 1..106
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT NON_TER 675
FT /evidence="ECO:0000313|EMBL:OAD07799.1"
SQ SEQUENCE 675 AA; 76216 MW; C61303724733D43C CRC64;
MGITFLEIES AQDLPPERNV TRTGFDMDPF VIVSYGVSTF RTRAIRHNLN PTWNEKLFFH
VRNSQENYKI KFAVYDKDKF SGNDFVASQE ISIADIIQKM PTSVTQSTAT PTAFDQADHS
PSQEIERNMG RHTIPLKLAK PDKWKDSVHP TLTIRAKFVP YVEIRKMFWI ALAKTCDADS
SNTMSRLEVQ AMLEALGSNI SESTLDHFWQ EHGKDFDQDL TMDELVASLE SFILAVDTKQ
DNGEDPNTII EEEKDVPVDA KNNSTSPDEA DYEALAEADG IQYIDGPLKE LKLQQDKEDD
HPHKPAQEKV IRLNECPICH KPNLGKRGQM DIVTHVATCA ANDWTTVDRF LMGNFGSEAQ
AQRKWFVKLV NKVGYGRYSA GKNNANIIVQ DRLTGQLIDE RMSVYVRLGM RLVYKGMRSG
IQSKTAQRIL ANMSVKQGRR FDNPLSKREI NSFIKFHQLD MSEVLEPLEN FNTFNEFFYR
KLKPGSRPCE SPDNKRVAVS PADCRMMAFP TIDSATNIWI KGVEFSIAKL LDDAEEAKAY
EGGALAIFRL APQDYHRYHS PVDGVIRKIH NVQGQYYTVN PMAIRTTLDV YGDNKRDIVH
METEAFGKVA IVCIGAMMVG SIVLTAGVGD HLARTDELGY FAFGGSTLVV LFEKNAMRFD
EDLLENASNS LETLV
//
