ID A0A162SXH6_9CRUS Unreviewed; 1293 AA.
AC A0A162SXH6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Cytoplasmic dynein 2 heavy chain 1 {ECO:0000313|EMBL:KZS21713.1};
GN ORFNames=APZ42_011677 {ECO:0000313|EMBL:KZS21713.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS21713.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS21713.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS21713.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS21713.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS21713.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LRGB01000024; KZS21713.1; -; Genomic_DNA.
DR STRING; 35525.A0A162SXH6; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703:SF22; CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1; 1.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858}.
FT DOMAIN 13..191
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 231..451
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 699..806
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 837..973
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 1013..1290
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT COILED 69..103
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 392..426
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1293 AA; 146014 MW; 97AD04D40DC7900D CRC64;
MLNNKNKEET LSFDARKISV DSRRAVEQLL NRRKESFDDK VARRASAAAA PLAAWVRANV
SYSRVLERIT PLEQEQANLR RNLQAAEDNM NRLATGLDDV DKQVALLRDQ LSVSTREASE
IEIGLKKARQ TLSVSQNLVL ELADEYDRWR LQLEELEQDR QNVAFHALLA AAFINFLSCS
TEDERKNSLS RWLTQLKLSQ HANITETGNE NEEVIFSLKN FLTSEQELML WRSEGLAADD
LAVDNALAIT QGTLYPHILD ATGKSIQWIM THFKSMTVET TSQRDERFAN ILDLAIRFGK
IIIIQDVDAI DPILFPILRN DYVIQGVRKL VRLGDKLVDW NDNFRLFLFS QSTGVAPMAS
PQANALVNTI NFNTTEAGLS EQLVALTVKH ENPELEQRKK QLLEQEEQLK LQLAQLEEKL
LQTLGNSRGN ILENTDVLTS LRQLKQSSAT IGQSLKESLA LQYSLEKERS TYNELAQFAS
RLFFAIRELS KLNHCYQFSV QAFMQIFLKN LDSKNVIESG PEKLGFIRQR LLKTVYTMVS
RAVFKPDKMV VAAHIVREMC GHIIQPNEWE LFVGQKSART QSNQIQLPSW IDESRLLSVS
ALKAVFPSIF AALHLEDTTL WSKSSTPIPP AISQALSPFQ QVLVVQAIYP EKLIDVLTQF
LSRTLELTEL FPATSSLRTI LNETCAAEPI LVLLPGDASG AYDMTVELEE LARDTLGDNR
LIEIAMGTDE TEKAAEFVRQ AAQNGHWICL KNVHLVTGWL PVLDRLINQL SGEESDDLHV
DFRLWMTAEP VSTLPLSLLQ RCKKIVSEAP QGMKRNLNRI MEAWNPSTLP GSPIHMQALF
VLAWFHAVVQ ERRNYVPQGW LKKHEFNESD LRAATEVLGQ AFREIDDSGN RWEYVNGLLL
NVIYGGRIDN SFDLRILRSY LVQYFNDDVL GKERFAINDE ITIPLSKSLR DYATIVRHLP
ETDKSSYFGL PPNIDTTVQY NQSIYLSACL KAFYQATAQP VAGDAKLLMN KLSPVFSTWK
SLLQGTSFLT NKDLVSSLSE NMQSNPLAAF VLAESALAVR LIHIVHHCLA AINRSLKSGL
PLSVSLMESA IDISSFKTPK SWYTLWEGPL QVEQFLRSLV KRARALTEEW LPSVQKSQLL
TNVLDLSELM NPEAFFSVHR QHSARELGIS MDSLQLLVLW DKPSLSKGQS RASAEITATL
NGIHIQGARM ASGVGIDECY PDTPSWNLIP HCYLSWLPVE DVKSSRTNGL HTVKVPLYVD
EERQRLITVL DIPFACGMID DWYRAGIALS LKD
//
