ID A0A162SYK7_9CRUS Unreviewed; 613 AA.
AC A0A162SYK7;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Putative Caspase-1 {ECO:0000313|EMBL:KZS21742.1};
GN ORFNames=APZ42_011731 {ECO:0000313|EMBL:KZS21742.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS21742.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS21742.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS21742.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS21742.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C14A family.
CC {ECO:0000256|ARBA:ARBA00010134, ECO:0000256|RuleBase:RU003971}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS21742.1}.
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DR EMBL; LRGB01000024; KZS21742.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162SYK7; -.
DR STRING; 35525.A0A162SYK7; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:InterPro.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1460; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR029030; Caspase-like_dom_sf.
DR InterPro; IPR033139; Caspase_cys_AS.
DR InterPro; IPR045133; IRE1/2-like.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR011600; Pept_C14_caspase.
DR InterPro; IPR002138; Pept_C14_p10.
DR InterPro; IPR001309; Pept_C14_p20.
DR InterPro; IPR015917; Pept_C14A.
DR InterPro; IPR000719; Prot_kinase_dom.
DR PANTHER; PTHR13954; IRE1-RELATED; 1.
DR PANTHER; PTHR13954:SF6; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR Pfam; PF00656; Peptidase_C14; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00376; IL1BCENZYME.
DR SMART; SM00115; CASc; 1.
DR SUPFAM; SSF52129; Caspase-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS01122; CASPASE_CYS; 1.
DR PROSITE; PS50207; CASPASE_P10; 1.
DR PROSITE; PS50208; CASPASE_P20; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000076858}.
FT DOMAIN 38..317
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 334..457
FT /note="Caspase family p20"
FT /evidence="ECO:0000259|PROSITE:PS50208"
FT DOMAIN 518..560
FT /note="Caspase family p10"
FT /evidence="ECO:0000259|PROSITE:PS50207"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 613 AA; 70857 MW; 4D1289F49D829627 CRC64;
MAEKGRRTLE EGAPLIKKPK ETTSIDKEIR EPVRQGHDCK LFCICTGKEN NVSKYLYISH
FPKKENKRPI YKGYYNCDVP VAIVRIDPIH SGTTKTEIDR ELLILKELEL HENFIRYFIH
EENENFVFIA TELCLCSVAD LLDPALEGKI PMAEKIREEL RAKEILRQAT NGLNYLHQNN
FVHRNIKPNN FLIKEINKTG NSTCRFAVKI TDFRLTRKLD LHKSSQSSGS AASEGWEAPE
SQKKEEDLNP KMDVFILGCF YHYVLIALSK NEANNGQLPF VPSDTEEERV VELMKKMLKF
KEKDRPTLQE ILENSYFKPC EDYKIYDNED KTKKPGLCVI FNQKKFKDSK QNRKGSNQDR
DALKVTFNGL GFDTQVHKNL ASFDVKNEIE NLAKGDFNNY GCLVVCFLSL GIENAILCYD
GRHVNTNELK YKFSLGNCPS LYGKPKIFII QACQGYLEQS QTGILSGKQR RRRSLPNLQD
LHLIDQQESS GSTVQLTNKD TKHTYEIEEL KKLKIWDYAK KNPPLMDFLT INATLPGFVS
YRHIYYGTYF VQALCKTLDE EYSGKKPVDG TNHMDLEGVL RRVQLNINRI YPRQTLLWEA
CLSKYIRFRG DTP
//
