ID A0A163ZKU2_9BRAD Unreviewed; 160 AA.
AC A0A163ZKU2;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Transcriptional repressor NrdR {ECO:0000256|HAMAP-Rule:MF_00440};
GN Name=nrdR {ECO:0000256|HAMAP-Rule:MF_00440,
GN ECO:0000313|EMBL:NUU40598.1};
GN ORFNames=A4A58_27240 {ECO:0000313|EMBL:KZD23595.1}, HB776_10905
GN {ECO:0000313|EMBL:QND71679.1}, HP556_05735
GN {ECO:0000313|EMBL:NUU40598.1};
OS Tardiphaga robiniae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Tardiphaga.
OX NCBI_TaxID=943830 {ECO:0000313|EMBL:KZD23595.1, ECO:0000313|Proteomes:UP000076574};
RN [1] {ECO:0000313|EMBL:KZD23595.1, ECO:0000313|Proteomes:UP000076574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Vaf07 {ECO:0000313|EMBL:KZD23595.1,
RC ECO:0000313|Proteomes:UP000076574};
RA Kopat V., Chirak E., Kimeklis A., Andronov E.;
RT "Microsymbionts genomes from the relict species Vavilovia formosa (Stev.)
RT Fed.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000515291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=581 {ECO:0000313|Proteomes:UP000515291};
RX PubMed=32686981;
RA Safronova V., Guro P., Sazanova A., Kuznetsova I., Belimov A., Yakubov V.,
RA Chirak E., Afonin A., Gogolev Y., Andronov E., Tikhonovich I.;
RT "Rhizobial microsymbionts of the narrowly endemic Oxytropis species growing
RT in Kamchatka are characterized by significant genetic diversity and possess
RT a set of genes that are associated with T3SS and T6SS secretion systems and
RT can affect the development of symbiosis.";
RL Mol. Plant Microbe 33:1232-1241(2020).
RN [3] {ECO:0000313|EMBL:QND71679.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=581 {ECO:0000313|EMBL:QND71679.1};
RX PubMed=33272987;
RA Hatmaker E.A., Presle G., Cannon O., Guss A.M., Elkins J.G.;
RT "Complete genome sequences of four natural Pseudomonas isolates that
RT catabolize a wide range of aromatic compounds relevant to lignin
RT valorization.";
RL Mol. Plant Microbe Interact. 9:1232-1241(2020).
RN [4] {ECO:0000313|EMBL:NUU40598.1, ECO:0000313|Proteomes:UP000570860}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 26467 {ECO:0000313|EMBL:NUU40598.1,
RC ECO:0000313|Proteomes:UP000570860};
RA Lemaire J.F., Inderbitzin P., Gregorio O.A., Collins S.B., Wespe N.,
RA Knight-Connoni V.;
RT "Genome Sequencing of Type Strains.";
RL Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Negatively regulates transcription of bacterial
CC ribonucleotide reductase nrd genes and operons by binding to NrdR-
CC boxes. {ECO:0000256|HAMAP-Rule:MF_00440}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_00440};
CC Note=Binds 1 zinc ion. {ECO:0000256|HAMAP-Rule:MF_00440};
CC -!- SIMILARITY: Belongs to the NrdR family. {ECO:0000256|HAMAP-
CC Rule:MF_00440}.
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DR EMBL; LVYV01000010; KZD23595.1; -; Genomic_DNA.
DR EMBL; JABMCJ010000071; NUU40598.1; -; Genomic_DNA.
DR EMBL; CP050292; QND71679.1; -; Genomic_DNA.
DR RefSeq; WP_068732542.1; NZ_LVYV01000010.1.
DR AlphaFoldDB; A0A163ZKU2; -.
DR STRING; 943830.A4A58_27240; -.
DR KEGG; trb:HB776_10905; -.
DR OrthoDB; 9807461at2; -.
DR Proteomes; UP000076574; Unassembled WGS sequence.
DR Proteomes; UP000515291; Chromosome.
DR Proteomes; UP000570860; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00440; NrdR; 1.
DR InterPro; IPR005144; ATP-cone_dom.
DR InterPro; IPR003796; RNR_NrdR-like.
DR NCBIfam; TIGR00244; transcriptional regulator NrdR; 1.
DR PANTHER; PTHR30455; TRANSCRIPTIONAL REPRESSOR NRDR; 1.
DR PANTHER; PTHR30455:SF2; TRANSCRIPTIONAL REPRESSOR NRDR; 1.
DR Pfam; PF03477; ATP-cone; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00440};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00440}; Metal-binding {ECO:0000256|HAMAP-Rule:MF_00440};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00440}; Reference proteome {ECO:0000313|Proteomes:UP000076574};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|HAMAP-Rule:MF_00440};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00440};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00440}; Zinc {ECO:0000256|HAMAP-Rule:MF_00440};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|HAMAP-
KW Rule:MF_00440}.
FT DOMAIN 49..139
FT /note="ATP-cone"
FT /evidence="ECO:0000259|PROSITE:PS51161"
FT ZN_FING 3..34
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00440"
SQ SEQUENCE 160 AA; 18424 MW; 836DE05165339270 CRC64;
MRCPNCNSLD TQVKDSRPAE DSAVIRRRRV CVTCNFRFTT FERVQLRELT VIKRNGRRVP
FDRDKLVRSL SISLRKRPVD PERVETMVSA IVRELESGGE AEISSETIGE IVMEHLRGLD
DVAYVRFASV YRNFREAKDF EAVLGELHAD DDGRPVVVRK
//
