ID A0A164AY38_9MICO Unreviewed; 590 AA.
AC A0A164AY38;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675};
DE EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675};
GN Name=bga_1 {ECO:0000313|EMBL:KZE88539.1};
GN ORFNames=AVP41_03043 {ECO:0000313|EMBL:KZE88539.1};
OS Microbacterium sp. TNHR37B.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=1775956 {ECO:0000313|EMBL:KZE88539.1, ECO:0000313|Proteomes:UP000076535};
RN [1] {ECO:0000313|EMBL:KZE88539.1, ECO:0000313|Proteomes:UP000076535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TNHR37B {ECO:0000313|EMBL:KZE88539.1,
RC ECO:0000313|Proteomes:UP000076535};
RA Adelskov J., Patel B.K.;
RT "Draft Genome Sequence of Microbacterium sp. TNHR37B isolated from the
RT Great Artesian Basin of Australia.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|RuleBase:RU000675};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZE88539.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LQGV01000004; KZE88539.1; -; Genomic_DNA.
DR RefSeq; WP_067166501.1; NZ_LQGV01000004.1.
DR AlphaFoldDB; A0A164AY38; -.
DR STRING; 1775956.AVP41_03043; -.
DR PATRIC; fig|1775956.3.peg.3052; -.
DR OrthoDB; 9813184at2; -.
DR Proteomes; UP000076535; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000675};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000675};
KW Reference proteome {ECO:0000313|Proteomes:UP000076535}.
FT DOMAIN 13..332
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 378..483
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 507..562
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 166
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 242
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 590 AA; 64343 MW; 413D8F9C9F51944E CRC64;
MTARTFEIGE RDFLLDGAPH RVISGALHYF RVHPDQWRER IRWGRMMGLN TIETYVAWNE
HSPEPGVAGA PARFDTEGRL DLARFLREVQ DEGMHAIVRP GPYICAEFDG GGLPAWLFRD
PEVGIRSLEP RFLAAVSDYL RSVMEIVAPL QIDRGGPVIL LQVENEYGAY GSDHDYLRAL
TDLFRDGGAT VPLTTVDQPV PEMLAAGTLP DLHATGSFGS RATERLAALR AQQPTGPLMC
SEFWCGWFDH WGAHHHTTDA ADSARELDAL LAAGASVNIY MLHGGTNFGL TNGANDKGVY
QPTVTSYDYD APLDEAGRPT EKFWAFRDVI SRYAPVPDLV REPVGPLPVP APAPLRYAGS
LDDLVPETGA GEWADLPTMD AAGIWRGLAR YRVSLDRGDA PVVLRFAEVR DRAWVRLDGL
PVATLARELH ENAVTLPRGT GVLDILVEDE GRVNYGERIG EPKGLIGPAT IEGVPVTGWR
VSRVPLEDLP TVAALPAAEI GLGAGVWRAT VDLDAPADLA LSTEGLGKGL AWFGEFFLGR
YWRKGPQQTL FVPAPATRAG SNVLTIVEFE SMASEAAAFV PDLRLGHTEH
//
