ID A0A164NS44_9NOCA Unreviewed; 646 AA.
AC A0A164NS44;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Acetoacetyl-CoA synthetase {ECO:0000313|EMBL:KZF08441.1};
GN ORFNames=A2J03_21490 {ECO:0000313|EMBL:KZF08441.1};
OS Rhodococcus sp. EPR-157.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=1813677 {ECO:0000313|EMBL:KZF08441.1, ECO:0000313|Proteomes:UP000077673};
RN [1] {ECO:0000313|EMBL:KZF08441.1, ECO:0000313|Proteomes:UP000077673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EPR-157 {ECO:0000313|EMBL:KZF08441.1,
RC ECO:0000313|Proteomes:UP000077673};
RA Ploux O.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZF08441.1}.
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DR EMBL; LVCV01000235; KZF08441.1; -; Genomic_DNA.
DR RefSeq; WP_068373267.1; NZ_LVCV01000235.1.
DR AlphaFoldDB; A0A164NS44; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000077673; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000077673}.
FT DOMAIN 36..91
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 102..462
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 529..604
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 646 AA; 69929 MW; BC085DD6CFF695B7 CRC64;
MTEPQWTPSS EDIQRARITD FATQVGQTYG LSFDDYAALW EWSKDNLEQF WQAVWDYFDI
ISDEDPTAVL GSAEMPGAQW FPGATLNYVE QVKRQVDRGG IAIQYVAEDG TERALSWDDL
ARQVGALAVT LTSAGVGTGD RVVGYLPNIP ETVVAFLATA TIGAIWSSCG QDYSASAALD
RLGQLDPKVL VTADGYSYGG KYHDRTADVT SLRAGLATVE SVIQVGEHVT EGSMSWTDAT
AGAHEWVSTP VPFDHPLWVV FSSGTTGLPK GIVHGHGGVL LEHLKSVALQ SDIGPEDTFF
WYTSPSWMMW NFQVAGLLVG ATIVCFAGSP GFPAPDALWS IAARERVTFL GTSPGYVLAC
IKADVHPSSE HDLSALRAVG ITGSSLPASS SIWLADNVGA HVPVFSISGG TDVVSAFVGG
ARTVPVWPGE LSAPYLGVAL DSFDERGESV RGDVGELVIT KPMPSMPIRF WNDVDGSRYR
GAYFDSFPGV WRHGDWITRT EHGSVVVHGR SDSTLNRNGI RMGSADIYQA VESLPEIVES
LVLGVESENG GYWMPLFVVL ADGTELDDEL RRKIKDVITE HASARHVPDE IIAAPGIPHT
RTGKKLEVPL KKIFQGRAQT GAFDRTSVDA PELVDWFVAR GRDHDR
//
