ID A0A165AIJ2_9CRUS Unreviewed; 580 AA.
AC A0A165AIJ2;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Histone-lysine N-methyltransferase trr {ECO:0008006|Google:ProtNLM};
GN ORFNames=APZ42_016268 {ECO:0000313|EMBL:KZS17710.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS17710.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS17710.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS17710.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS17710.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS17710.1}.
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DR EMBL; LRGB01000614; KZS17710.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A165AIJ2; -.
DR STRING; 35525.A0A165AIJ2; -.
DR EnsemblMetazoa; XM_045173834.1; XP_045029769.1; LOC116923682.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0043933; P:protein-containing complex organization; IEA:UniProt.
DR CDD; cd19171; SET_KMT2C_2D; 1.
DR Gene3D; 3.30.160.360; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR003889; FYrich_C.
DR InterPro; IPR003888; FYrich_N.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45888; HL01030P-RELATED; 1.
DR PANTHER; PTHR45888:SF6; HL01030P-RELATED; 1.
DR Pfam; PF05965; FYRC; 1.
DR Pfam; PF05964; FYRN; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00542; FYRC; 1.
DR SMART; SM00541; FYRN; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS51543; FYRC; 1.
DR PROSITE; PS51542; FYRN; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 27..135
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 441..557
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 564..580
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 359..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 65398 MW; 2FC3A5FC87B5B99B CRC64;
MTENELTEML YRAAICIRPA ADKATDKRQC LFCYGQGDGV SDGPARLINF DVDRWVHLNC
ALWHEEVFEM VNGALMNVDT ALKQSLTQTC VHCGRNGASV KCFKLRCSSV FHLGCAVKEG
CVFLKNKSVY CSQHLPKCSS TSSTSVVDIK EEQLTTLSVF RRVYINRDEN RQVATVMHSG
GVAGPLSQLD AGEQSYLLRV GSLTFLSVGQ LLPHQLAAFH SPNCIYPIGY QVVRFYWSPR
QIHKRCRYLC SIEDCEGRPQ FNVVVQEPDR PHLPDLFFKD WTCQGVWQQI LGAIEEMRRQ
EGVVRLFPQF LNGEDLFGLT EPAIVRVLES LPGIESLTDY NFKYGRNPLL ELPLAVNPTG
SARSEPKLRT HVKRFHAQRT TGTSRSSSNT SASSSGGGGS GSYSNSLSSG LVMVDLPGPY
SKQFVHSKSS QYKKMKQEWR HNIYLARSKI QGLGLYAARD IEKHTMVIEY IGEMIRAELA
ECREKRYEAA NRGIYMFRLD EQRVIDATLC GGLARYINHS CGPNCVAEAV EVERDLRIII
FASRRISRGE ELSYDYKFDI EDDHKIPCLC GAPSCRKWMN
//
