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Database: UniProt
Entry: A0A166D2E2_DAUCA
LinkDB: A0A166D2E2_DAUCA
Original site: A0A166D2E2_DAUCA 
ID   A0A166D2E2_DAUCA        Unreviewed;       819 AA.
AC   A0A166D2E2;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   07-JUN-2017, entry version 5.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=DCAR_005476 {ECO:0000313|EMBL:KZN04639.1};
OS   Daucus carota subsp. sativus.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; asterids; campanulids; Apiales; Apiaceae; Apioideae;
OC   Scandiceae; Daucinae; Daucus; Daucus sect. Daucus.
OX   NCBI_TaxID=79200 {ECO:0000313|EMBL:KZN04639.1, ECO:0000313|Proteomes:UP000077755};
RN   [1] {ECO:0000313|EMBL:KZN04639.1, ECO:0000313|Proteomes:UP000077755}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DH1 {ECO:0000313|Proteomes:UP000077755};
RC   TISSUE=Leaf {ECO:0000313|EMBL:KZN04639.1};
RX   PubMed=27158781; DOI=10.1038/ng.3565;
RA   Iorizzo M., Ellison S., Senalik D., Zeng P., Satapoomin P., Huang J.,
RA   Bowman M., Iovene M., Sanseverino W., Cavagnaro P., Yildiz M.,
RA   Macko-Podgorni A., Moranska E., Grzebelus E., Grzebelus D.,
RA   Ashrafi H., Zheng Z., Cheng S., Spooner D., Van Deynze A., Simon P.;
RT   "A high-quality carrot genome assembly provides new insights into
RT   carotenoid accumulation and asterid genome evolution.";
RL   Nat. Genet. 48:657-666(2016).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KZN04639.1}.
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DR   EMBL; LNRQ01000002; KZN04639.1; -; Genomic_DNA.
DR   RefSeq; XP_017236115.1; XM_017380626.1.
DR   GeneID; 108209624; -.
DR   Proteomes; UP000077755; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000077755};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077755};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    423    446       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    467    485       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    548    566       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    586    603       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    632    655       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    756    777       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED       99    126       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   819 AA;  93612 MW;  4475BD1E5ADE863E CRC64;
     MNYVDSLPDM DLMRSEKMTF VQLIIPVESA HRAVTYLGEL GLLQFRDLNA DKSPFQRTFV
     NQVKRCAEMS RKLRFFKDQI HKASLGSPIQ AGMQPDIELE ELEIQLAEHE HELNEMNSNS
     EKLQHTFNEL VEFKMVLEKA GDFLLSSKGH PVDEDRELEE HAYSNNDYSD SASLLELETQ
     PGPSSSQSGL RFISGIISKS KVLRFERILF RATRGNMLFN QSTADDPIMD PLSTEMVEKT
     VFVVFFSGEQ AKTKILKICE AFGANCYPVP EDITKQRQIT REVLSRLSEL ETTLDAGIRH
     RNKALTSISF HLTKWLKMVK REKAVFDTLN MLNFDVTKKC LVGEGWCPIF AKAQIQEALR
     RATFDSSSQV GIIFHAMDAL EAPPTYFRTN SFTNAYQEIV DAYGVARYQE ANPAVYTVIT
     FPFLFAVMFG DWGHGICLLL GALFLIAREN KFSSQKLGSF MEMLFGGRYV LLLMSLFSIY
     CGLIYNEFFS VPYHIFGGSA YRCRDDSCSN AYTVGLIKFR DPYPFGVDPS WRGSRSELPF
     LNSLKMKMSI LLGVAQMNLG IMLSYFDARF FGNSLDIKYQ FVPQIIFLNS LFGYLSLLIL
     IKWCTGSQAD LYHVMIYMFL SPFDDLGDNQ LFWGQGVVQV MLLLAALVAV PWMLFPKPFI
     LKKLHSERFQ GRTYGVLRTS EVDLDSEPDS ARQHIEEFNF SEIFVHQMIH SIEFVLGAVS
     NTASYLRLWA LSLAHSELST VFYEKVLLLA WGYDNILIRL VGLAVFAFAT AFILLMMETL
     SAFLHALRLH WVEFQNKFYH GDGYKFRPFS FATLTDDDE
//
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