ID A0A166DFS4_9EURY Unreviewed; 469 AA.
AC A0A166DFS4;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE {ECO:0000256|ARBA:ARBA00013280};
GN Name=nifD_2 {ECO:0000313|EMBL:KZX15555.1};
GN ORFNames=MBCUT_14270 {ECO:0000313|EMBL:KZX15555.1};
OS Methanobrevibacter cuticularis.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX NCBI_TaxID=47311 {ECO:0000313|EMBL:KZX15555.1, ECO:0000313|Proteomes:UP000077275};
RN [1] {ECO:0000313|EMBL:KZX15555.1, ECO:0000313|Proteomes:UP000077275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11139 {ECO:0000313|EMBL:KZX15555.1,
RC ECO:0000313|Proteomes:UP000077275};
RA Poehlein A., Seedorf H., Daniel R.;
RT "Genome sequence of Methanobrevibacter cuticularis DSM 11139.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC prosthetic group of nitrogenase (FeMo cofactor).
CC {ECO:0000256|ARBA:ARBA00003171}.
CC -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005155}.
CC -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family.
CC {ECO:0000256|ARBA:ARBA00011002, ECO:0000256|RuleBase:RU004021}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZX15555.1}.
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DR EMBL; LWMW01000115; KZX15555.1; -; Genomic_DNA.
DR RefSeq; WP_067259998.1; NZ_LWMW01000115.1.
DR AlphaFoldDB; A0A166DFS4; -.
DR STRING; 47311.MBCUT_14270; -.
DR PATRIC; fig|47311.3.peg.1558; -.
DR OrthoDB; 61861at2157; -.
DR UniPathway; UPA00782; -.
DR Proteomes; UP000077275; Unassembled WGS sequence.
DR GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR Gene3D; 3.40.50.12380; Nitrogenase MoFe cofactor biosynthesis protein NifE, C-terminal; 1.
DR Gene3D; 3.40.50.1980; Nitrogenase molybdenum iron protein domain; 1.
DR InterPro; IPR000510; Nase/OxRdtase_comp1.
DR InterPro; IPR000318; Nase_comp1_CS.
DR InterPro; IPR005973; NifE.
DR NCBIfam; TIGR01283; nifE; 1.
DR PANTHER; PTHR42956; NITROGENASE IRON-MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN NIFE; 1.
DR PANTHER; PTHR42956:SF1; NITROGENASE IRON-MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN NIFE; 1.
DR Pfam; PF00148; Oxidored_nitro; 1.
DR SUPFAM; SSF53807; Helical backbone' metal receptor; 1.
DR PROSITE; PS00699; NITROGENASE_1_1; 1.
DR PROSITE; PS00090; NITROGENASE_1_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nitrogen fixation {ECO:0000256|ARBA:ARBA00023231,
KW ECO:0000256|RuleBase:RU004021};
KW Oxidoreductase {ECO:0000313|EMBL:KZX15555.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077275}.
FT DOMAIN 48..446
FT /note="Nitrogenase/oxidoreductase component 1"
FT /evidence="ECO:0000259|Pfam:PF00148"
FT COILED 305..332
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 469 AA; 52080 MW; D027C947DEF478E1 CRC64;
MEQENSSTEP IIKTFKSREK HMCIKRGNLS LPECDTPGIP GTVTQRTCVF GGARIVLMPI
TDALHLVHGP IGCASCTWDI RGSKSSDSKL YKQGCSSDLK EKDIIFGGER KLYDSIIELH
KLHDPGAIFV YATCVSGVIG DDIKSVCNEA ERITSCRVIP VQSEGFQDHN KTKGHWIGCD
ALIDSVIGTS EMGVEDATPF DINILGEFNV AGDLWGIKPL LEYLGLNIIS AITGDSKVEE
IAKSHHAKLN IVQCQKSSNY LAKKMEKKYG IPSLKVNFFG IESTITSITE IVEFFDHEEM
KIKANNLIEN GLKNLDEKLR EYKQRLNGKT VALYVGGNKA WSLVRAFEEL GMNVIMSGTK
NGIKEDYENI RDVVKEGTLI VDDANSTELM RLLKKYKPNL LISGAKEKYI ALKLGVSFCD
FNHDRISAFA GFKGFLEFAK EVDAAVSTSV WNIVKTELRQ KSIKEDIHV
//
