ID   A0A166S1M0_9EURY        Unreviewed;      1561 AA.
AC   A0A166S1M0;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Histidine kinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=A4G99_12275 {ECO:0000313|EMBL:KZN23655.1};
OS   Haladaptatus sp. R4.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haladaptataceae; Haladaptatus.
OX   NCBI_TaxID=1679489 {ECO:0000313|EMBL:KZN23655.1, ECO:0000313|Proteomes:UP000076599};
RN   [1] {ECO:0000313|EMBL:KZN23655.1, ECO:0000313|Proteomes:UP000076599}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R4 {ECO:0000313|EMBL:KZN23655.1,
RC   ECO:0000313|Proteomes:UP000076599};
RA   Mukhopadhyay S.K.;
RT   "Genome sequence of halophilic archaea.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KZN23655.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LWHG01000028; KZN23655.1; -; Genomic_DNA.
DR   STRING; 1679489.A4G99_12275; -.
DR   OrthoDB; 342253at2157; -.
DR   Proteomes; UP000076599; Unassembled WGS sequence.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 2.10.70.100; -; 1.
DR   Gene3D; 3.30.450.40; -; 4.
DR   Gene3D; 3.30.450.20; PAS domain; 5.
DR   InterPro; IPR031803; BAT_GAF/HTH-assoc.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR007050; HTH_bacterioopsin.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR013655; PAS_fold_3.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR34236; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR   PANTHER; PTHR34236:SF1; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR   Pfam; PF15915; BAT; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF13185; GAF_2; 3.
DR   Pfam; PF04967; HTH_10; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF13188; PAS_8; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00065; GAF; 4.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 4.
DR   SUPFAM; SSF55781; GAF domain-like; 4.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 5.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Transcription {ECO:0000256|ARBA:ARBA00023015};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          413..485
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          490..545
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   COILED          250..277
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1561 AA;  175812 MW;  E57FCB82116A3D52 CRC64;
     MAEWPTELRV AVDLMLGADE AIGIYWGEDL VLLYNDAARE QIGKKHPNAL GRPARDVFPE
     AWEFLGPMHE QVMAGKGPVR VEDQYLPIER GDAIEDVWWD SSFNPIPLAD GSVGGVFNIS
     VDITDRVQIE AALRESNERL QVALNAAEMG TWEWDLEART VDGDDTMLSL FDLPPTDEPV
     PVEQFLVKES DEGTDQAEDT MEFSFEPGEE IQDEVELEGV DTPRWISWRG RASADDPTVL
     RGVSFDITDR KQAEIEREQA IEELRESEER YRTLFDSINE SIQEGFCIVE LPEEGEAADE
     ASTGGTVGGR REPDDYRFVE ANPTFEELTG VTDVVGARWS DMDVDGDFPG FDVCAEVART
     GESQRVETTG EPLIDGWFDV RVFPYGSSDS RQVAVLIEDI TEQKETEAAL RENEKRLRLA
     ADIGNIAVFE WDLETDRVRG NERMNELFGY DKHEIIVGAE LLEERIHPDD LDSVVGRLEE
     VFESASDGNY EFEFRAMRPD GSDRWVLTNG EVFFEEDGDD RRAVRVFGTG IDITEQKQRE
     ERQEFLLRFS DALRAQPDAE SIKDRAVEML AENLDLDRCW ISEVFEQRGI STVGPEQIRP
     DLPEMAGVFQ LSEYPETMRQ LATQPMVVQD ADNDPHFSDS EKELLAGYDL RSLLVAPLRE
     GEDDVIWALA AAMAKPRHWT NGERALLEDA AERTWAAVER TRAEQELADE LAATRELQDI
     STTLIGEDDI ETLSQHVLDA ASEMMDADFG SVQLYDPDRH DLELVANRGF TAETEAAWQR
     VTPEHGTACG KALKTGERVI VSDVESSEFI AGTGDLETFR QNGIQAVQTT PFVSRSGDMI
     GMFSTHWETP RDLSESDLGR LDVLARQAAD LIEHRQITEA LRESEERYRM LFESIIEGFC
     IIEVLFDEED EPVDYRFLET NPAFEDQTGL IDAEGKRMKE LEPNHEDHWF ETYGRIAKTG
     EPERFTNPAK HLNDRWYDVN AFRVGDPEER KVAIAFKDIS DSKRFQIALE RLNDASQELI
     DANPEGVKDR TADIVRDVLN VEYAALWRYD KTVGELDEYA SQTAPEMPEN SVRLPAEFSE
     RVWQTFIGDD IDVVNDTDIP ENEPVAPPLR SRVLIPLGRH GVICAGSTRA EIFDDQKLDL
     LETVSTTIET AWDRADGQEE LTRQNKELTH LDGLNTLIRK IDQALVEAET VDVIDEAVCE
     RLAHSELFEF AWIGEFDADD NAVNPRAWAG VDSRSLDDLT TEVDGPVSER RPFTAAIQTK
     KRQVVNDIAT DAEAAPWREV ALDLGARSCL CLPLVYDDFV YGIVTVYNGT PQHDERDIDV
     LVELGRTIAN AIHAVETREA HHMNRVVELT FRSTAADTPL CQLAQETGCV MEITGLVPGA
     DGETTVFFTA TDVSSGALVT AGEQSLAIGE LICLSEREDE SLFKARLAES TLTSWFRNRD
     AMMRSLTIDN GTATLVLDVP TSVDIRRFFE TGQQAIPDLE LLARRTHTRS SNTTHTLQTA
     FTERLTDRQQ EILQLAYRSG FFESPRLQTG NELSTALDLS QSTFNYHLRG AERRLLEVVF
     D
//