ID   A0A166UNV7_9RHOB        Unreviewed;       679 AA.
AC   A0A166UNV7;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN   ORFNames=A3721_12395 {ECO:0000313|EMBL:KZY06245.1};
OS   Sulfitobacter sp. HI0023.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Sulfitobacter.
OX   NCBI_TaxID=1822225 {ECO:0000313|EMBL:KZY06245.1, ECO:0000313|Proteomes:UP000077323};
RN   [1] {ECO:0000313|EMBL:KZY06245.1, ECO:0000313|Proteomes:UP000077323}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HI0023 {ECO:0000313|EMBL:KZY06245.1,
RC   ECO:0000313|Proteomes:UP000077323};
RA   Sosa O.A.;
RT   "Microbial cycling of marine high molecular weight dissolved organic
RT   matter.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KZY06245.1}.
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DR   EMBL; LWEQ01000017; KZY06245.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A166UNV7; -.
DR   Proteomes; UP000077323; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077323};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        301..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        328..347
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        359..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          420..552
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   679 AA;  72245 MW;  D6E1049D6746B384 CRC64;
     MVDIDEASLR ELGQWPWPRT FVAELTDRLF ASGAVAVGFD ILFTEPDRTS PDAVLRNMQR
     FARGTARLPA DLAGQNNDEN LAAAIAGRPV VLALAGAPRG EVPAPKAGIS FTGARPDSAV
     TSYPGALAPL PVLTDAAAGL GVISLGAGND GISRGVPMVA RMGDRLMPSL AAELLRVAQG
     ARSHILKTSE ASGEVSGGTA RVVAMRTGGA EYPLDGNGEL RLHFTEETEN RMTPAHLVLN
     DTALPGLQPA IAGRIILVGS SAQGLFDLRR TPLSASVPGV LLQADVLEQV LAQTFLTRPD
     WMPGLELVLL LLAGLTVTFL CTKDKPMAAL IGLAVLGIAA ALGGWQAFAR AGLLFDPSLI
     VITGFATLLP GSALGLIGKE RMRAKIRSRF AYFVPGTLVD EIAADPGHAL TPNGASREMT
     VMFVDMRRFS TVTEKMSPED VVRLLNRYLG AVSDAMMEHG ATIDKYIGDA IMAFWNAPLP
     QADHRARALA TIFAIEDHVA EANALLEAEG LPAVGIGLGI NTGQAFVGLM GSRDRLSYTC
     VGDSVTQAAR FEGLTRLYGT INCVGADTVA ALPDDMRSVM LDKVVVKGRK EPVALHTVYK
     AENTEFHAAA KSFEDARNAY LAREWDRALE HLAALSARQV TGFETDRLAD LYRERIAVLR
     NTDLPPEWDG TFVADSKRG
//