ID A0A166XYY5_9HYPO Unreviewed; 521 AA.
AC A0A166XYY5;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Phosphomethylpyrimidine kinase type-1 {ECO:0000313|EMBL:OAA36348.1};
GN ORFNames=BBO_08225 {ECO:0000313|EMBL:OAA36348.1};
OS Beauveria brongniartii RCEF 3172.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria;
OC Beauveria brongniartii.
OX NCBI_TaxID=1081107 {ECO:0000313|EMBL:OAA36348.1, ECO:0000313|Proteomes:UP000076863};
RN [1] {ECO:0000313|EMBL:OAA36348.1, ECO:0000313|Proteomes:UP000076863}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCEF 3172 {ECO:0000313|EMBL:OAA36348.1,
RC ECO:0000313|Proteomes:UP000076863};
RX PubMed=27071652; DOI=10.1093/gbe/evw082;
RA Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT "Divergent and convergent evolution of fungal pathogenicity.";
RL Genome Biol. Evol. 8:1374-1387(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA36348.1}.
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DR EMBL; AZHA01000036; OAA36348.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A166XYY5; -.
DR OrthoDB; 5477821at2759; -.
DR Proteomes; UP000076863; Unassembled WGS sequence.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0050334; F:thiaminase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01169; HMPP_kinase; 1.
DR CDD; cd19367; TenA_C_ScTHI20-like; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 1.20.910.10; Heme oxygenase-like; 1.
DR InterPro; IPR016084; Haem_Oase-like_multi-hlx.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR004305; Thiaminase-2/PQQC.
DR InterPro; IPR027574; Thiaminase_II.
DR NCBIfam; TIGR00097; HMP-P_kinase; 1.
DR NCBIfam; TIGR04306; salvage_TenA; 1.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR Pfam; PF03070; TENA_THI-4; 1.
DR SUPFAM; SSF48613; Heme oxygenase-like; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:OAA36348.1};
KW Transferase {ECO:0000313|EMBL:OAA36348.1}.
FT DOMAIN 13..288
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
FT DOMAIN 311..517
FT /note="Thiaminase-2/PQQC"
FT /evidence="ECO:0000259|Pfam:PF03070"
SQ SEQUENCE 521 AA; 56548 MW; 207D288127C60AA3 CRC64;
MVQGRVLVVA GSDPSGGAGL EADQKVLAAH QCYAMTATTA LTVQNTKGVM GVHVVPAEFV
GRQIDAVVED IGVDVVKTGM LGSVETIDVL SDMIEKHNLT TVVVDPVMIS TSGARLLPHE
AIKHLSDRLL ARTTLLTPNV PEAKLLLAEN CIAEQRPNNN NNVGGVEELE ALAQTIRDRL
GPRWVLVKGG HVPLRAADMT AAAGDEDKDA DKVVVDVLVG PEGEVVKVQS PFQPSTSTHG
TGCSLASAIS AHLAKGQDVP TAVRAACRYV AAGIRTAPQL GGGNGPLNHF HSSYALPFSP
GYFVEYLLER PDVRRMWKEF VQHPFVMALG NGTLPLDSFK GYIIQDYLFL VQFARANSLA
AYKAKNIIDI QRSNEIVSHI VREMDLHINY CKGFGISEQE IQATPELQAC TAYTRYVLDI
GQSEDLLALQ MALAPCLLGY GAVAQMLAAH PATVRDQQAN TYWPWIETYG AADYVEAVRL
GSDLIEKKIR DCSPARIEEL VKIFIHGTRM EIGFWEMFPS K
//
