ID   A0A167B9E8_9PEZI        Unreviewed;       984 AA.
AC   A0A167B9E8;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
GN   ORFNames=CI238_03315 {ECO:0000313|EMBL:KZL81049.1};
OS   Colletotrichum incanum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC   Colletotrichum spaethianum species complex.
OX   NCBI_TaxID=1573173 {ECO:0000313|EMBL:KZL81049.1, ECO:0000313|Proteomes:UP000076584};
RN   [1] {ECO:0000313|EMBL:KZL81049.1, ECO:0000313|Proteomes:UP000076584}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MAFF 238704 {ECO:0000313|EMBL:KZL81049.1,
RC   ECO:0000313|Proteomes:UP000076584};
RA   Hacquard S., Kracher B., Hiruma K., Weinman A., Muench P., Garrido Oter R.,
RA   Ver Loren van Themaat E., Dallerey J.-F., Damm U., Henrissat B.,
RA   Lespinet O., Thon M., Kemen E., McHardy A.C., Schulze-Lefert P.,
RA   O'Connell R.J.;
RT   "Survival trade-offs in plant roots during colonization by closely related
RT   pathogenic and mutualistic fungi.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KZL81049.1}.
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DR   EMBL; LFIW01001782; KZL81049.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A167B9E8; -.
DR   STRING; 1573173.A0A167B9E8; -.
DR   Proteomes; UP000076584; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR12673; FACIOGENITAL DYSPLASIA PROTEIN; 1.
DR   PANTHER; PTHR12673:SF267; GUANYL NUCLEOTIDE EXCHANGE FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13320)-RELATED; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50010; DH_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000076584}.
FT   DOMAIN          242..483
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          185..204
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          821..853
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          910..970
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..41
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        839..853
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        927..952
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   984 AA;  108869 MW;  A7E67E1F952206E4 CRC64;
     MALPPDSASL GSCSRSSSVR INRKTSCATS SPPSPGSQHE STKSEDVFDN VDLSSGLDGL
     HIDGVEVWDT LSSMAAFGLE PNNGDSYDDL VLLPRISVDD SDDALELSDS DMPPKRGPFH
     RWMRNLHRRA KQRPRPMNAD SVLPWKLLDS ADRSALSRRT RHRRSSSGSS FGFVAAVKSA
     SVSLASGSTA TRPRGNSHRS LAYSKTDRSS RASFTAARFS EDSCHVEWPA NIDPLATERA
     LQRRRILEEL ISTEEGYIRD LRFLMNVYIT ILASLPTLPM GLRSSINRNL TDIVELHEEL
     LGELHRVVPD SEYTQIEIPP LPSKVTGHGH QRLRSLDSVP EDDNRAISWL QDVPGMISEA
     QIAGDVAKMN RFFIYEEYGA KYELMIKDVA SAHRTMPQWD TYQRGIEALA SSLGPASTHT
     DQSKKSLTIG DLLVKPIQRI CKYPLLFAEL LKYTPVADCP NSHMEVESAL LRLREATAEI
     NRATSDRRIK STLEKTWILQ DRLVFPEQAR RKKLDAASKN RIRSFGHVEL CGALHVCWQS
     KEGAKGRYMI CLLYSNVLCL ASASKVDQIY TIQACINLGS IKIEETDNGR GLQCHTAPFS
     WKLVFECDSQ LYELLMTACS PREQEEWRSR LSNAAKAERE QTDPNLYSSM SLGMKSLGTV
     FRKPGVFSQS NNDRSVSLTG ISGTVARRIS IHRATTVGPK SPLCQVVLKN TSVVRDNSDA
     ASNSSINRSQ SLLTTNPRIP ILAPPRGERA RLEALMSDIW SRDTLPFPGM TGRSRSEHLV
     RSSASTMMRK LSVASIASSF AKRSNSVASL GKLVVEDDTG DKETMHYGHP PKLCRAESSN
     TEHGPDDGVD ETAKTRLPKI DDDIEVTSTV SAPATPMLVQ SNIVVHADPV EQLRSGYVGL
     MLSGDVLPSR PTVLRTASGN NLPRVRRDPP TPKRSPCPSE RDGKDHQGRA PKAPKLSHKP
     SMRWGKVGTL NKDDLVQGIR SFFR
//