ID A0A167FC71_9BACL Unreviewed; 261 AA.
AC A0A167FC71;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Spectinomycin 9-adenylyltransferase {ECO:0000256|PIRNR:PIRNR000819};
GN ORFNames=PNBC_03015 {ECO:0000313|EMBL:OAB76400.1};
OS Paenibacillus crassostreae.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1763538 {ECO:0000313|EMBL:OAB76400.1, ECO:0000313|Proteomes:UP000077134};
RN [1] {ECO:0000313|EMBL:OAB76400.1, ECO:0000313|Proteomes:UP000077134}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LPB0068 {ECO:0000313|EMBL:OAB76400.1,
RC ECO:0000313|Proteomes:UP000077134};
RA Shin S.-K., Yi H.;
RT "Paenibacillus sp. LPB0068, isolated from Crassostrea gigas.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + spectinomycin = 9-O-adenylylspectinomycin + diphosphate;
CC Xref=Rhea:RHEA:63228, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:146260, ChEBI:CHEBI:146261;
CC Evidence={ECO:0000256|ARBA:ARBA00001672,
CC ECO:0000256|PIRNR:PIRNR000819};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAB76400.1}.
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DR EMBL; LSFN01000005; OAB76400.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A167FC71; -.
DR STRING; 1763538.LPB68_00520; -.
DR KEGG; pcx:LPB68_00520; -.
DR OrthoDB; 5643411at2; -.
DR Proteomes; UP000077134; Unassembled WGS sequence.
DR GO; GO:0070566; F:adenylyltransferase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR CDD; cd05403; NT_KNTase_like; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR024172; AadA/Aad9.
DR InterPro; IPR025184; AadA_C.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR041633; Polbeta.
DR Pfam; PF13427; AadA_C; 1.
DR Pfam; PF18765; Polbeta; 1.
DR PIRSF; PIRSF000819; Streptomycin_3-adenylyltransf; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251,
KW ECO:0000256|PIRNR:PIRNR000819};
KW ATP-binding {ECO:0000256|PIRNR:PIRNR000819};
KW Nucleotide-binding {ECO:0000256|PIRNR:PIRNR000819};
KW Nucleotidyltransferase {ECO:0000256|PIRNR:PIRNR000819};
KW Reference proteome {ECO:0000313|Proteomes:UP000077134};
KW Transferase {ECO:0000256|PIRNR:PIRNR000819}.
FT DOMAIN 22..77
FT /note="Polymerase beta nucleotidyltransferase"
FT /evidence="ECO:0000259|Pfam:PF18765"
FT DOMAIN 147..247
FT /note="Adenylyltransferase AadA C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13427"
SQ SEQUENCE 261 AA; 30307 MW; D79513E3B5DD1DB5 CRC64;
MEKQINLDSV VELFKKELSD VLIGIYLHGS MAMKCFNPSH SDIDLLIITR DKSPIETYQR
IAKQLIVIEE EEIKIAKGLE LSIILERNFK DFVYPTPFEF HYSAFHKERY KNEEFYFCGG
YDDPDLAAHF VVAYNRGITL YGRPFNEIFN LIDKKYYVNS ITSDVKNAQE EIVDNPIYYV
LNLCRALQYL HESTISSKKE GGEWALGILP KKYVDLVDKC LASYNNASIS LELNNQFLLD
FAEYMINNID NSKLNSRNED V
//
