ID A0A167N6P2_PHYB8 Unreviewed; 704 AA.
AC A0A167N6P2;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Choline/carnitine acyltransferase domain-containing protein {ECO:0000259|Pfam:PF00755};
GN ORFNames=PHYBLDRAFT_167469 {ECO:0000313|EMBL:OAD75150.1};
OS Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC
OS 33097 / NRRL 1555).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Phycomycetaceae; Phycomyces.
OX NCBI_TaxID=763407 {ECO:0000313|EMBL:OAD75150.1, ECO:0000313|Proteomes:UP000077315};
RN [1] {ECO:0000313|Proteomes:UP000077315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1555(-) {ECO:0000313|Proteomes:UP000077315};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA McCluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232, ECO:0000256|RuleBase:RU003801}.
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DR EMBL; KV440978; OAD75150.1; -; Genomic_DNA.
DR RefSeq; XP_018293190.1; XM_018435646.1.
DR AlphaFoldDB; A0A167N6P2; -.
DR STRING; 763407.A0A167N6P2; -.
DR GeneID; 28996552; -.
DR VEuPathDB; FungiDB:PHYBL_167469; -.
DR InParanoid; A0A167N6P2; -.
DR OrthoDB; 1429709at2759; -.
DR Proteomes; UP000077315; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22589:SF29; MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00439; ACYLTRANSF_C_1; 1.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003801};
KW Reference proteome {ECO:0000313|Proteomes:UP000077315};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003801}.
FT DOMAIN 30..625
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 334
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 704 AA; 79810 MW; 905013C8FB0E1EA6 CRC64;
MANVKAHKNA LNFEPSGGET FRYQEQLPKL PIPELKDTLA RYLTSIQPLQ SVEEHERSKV
AVKDFLENDG PKLQSKLLTY ATDKSSYIEE FWYDSYLQHS DPVVLNLNPF FVLEDDPTPL
RNDQVIRASS LIYSTLKFID ALHDKTLEPD VFRGTPLCMS QFSRLFGTAR VPTDNGCYMA
PGNESRHIVV MAHSQSYHFE VFDEFGETAL TEKEIAANLR AILRDAARIP VSDIAKTAIG
VLTTEKRRNW ARLRAELKSD PTNRQSLKVI DSALFIVCLD HVEPTTIEDL SSNMLCGTYR
LDQGLQVGTC TNRWYDKLQI IVCKNGSAGI NFEHTGVDGH TVLRYVSDIY TDTILRFAKT
INSQTKSIFH SHKQKDSAAN RARRDSFGTG LSFDINPRRI EWNMTEPITL GVRYAETRLS
DLILQNEVRV LEFNNYGKYF ITDMKMSPDA FVQMAFQAAY YGLYGKSECT YEPAMTKTFL
HGRTEAIRSV TNASVNFVET YYSKAADHDK LESLRKALKS HTNLTRQCAQ GLGQDRHLFA
LECLWNRMNK DTKKPLIFTD SGWKVLGHTM ISTSNCGNPA LRLFGFGPTV SDGFGIGYII
KEDGISFAAS SKHRQTERLL KTLEKYLLDI QIMLQKEKYP GGISQRQRIL AMENADELNN
GYSYFDNGEN FGSDKESSSG SIDGYLSRSP TRKVGKRLML RETD
//
