ID A0A168GWS1_CORDF Unreviewed; 733 AA.
AC A0A168GWS1;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Rad4 family protein {ECO:0000313|EMBL:OAA77017.1};
GN ORFNames=LEL_06701 {ECO:0000313|EMBL:OAA77017.1};
OS Akanthomyces lecanii RCEF 1005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Akanthomyces;
OC Cordyceps confragosa.
OX NCBI_TaxID=1081108 {ECO:0000313|EMBL:OAA77017.1, ECO:0000313|Proteomes:UP000076881};
RN [1] {ECO:0000313|EMBL:OAA77017.1, ECO:0000313|Proteomes:UP000076881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCEF 1005 {ECO:0000313|EMBL:OAA77017.1,
RC ECO:0000313|Proteomes:UP000076881};
RX PubMed=27071652; DOI=10.1093/gbe/evw082;
RA Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT "Divergent and convergent evolution of fungal pathogenicity.";
RL Genome Biol. Evol. 8:1374-1387(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPC family. {ECO:0000256|ARBA:ARBA00009525}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA77017.1}.
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DR EMBL; AZHF01000004; OAA77017.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A168GWS1; -.
DR STRING; 1081108.A0A168GWS1; -.
DR OrthoDB; 181129at2759; -.
DR Proteomes; UP000076881; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR018327; BHD_2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR PANTHER; PTHR12135:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10404; BHD_2; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01031; BHD_2; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000076881}.
FT DOMAIN 407..465
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 467..530
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01031"
FT DOMAIN 537..611
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 173..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 662..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..225
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 733 AA; 82952 MW; F4A8B23967D5C449 CRC64;
MLSHLPPKMW DEVDRWKEKS GLVQPTTGKS KGKRKGRIAA KARDWNKNAE KLEEGVPDMS
NGDPLFRLGQ ALMSWWKQRY RTTAPGLRKW GYMALERLDR LHKAYANEEQ DANRFGERLE
SIDDLRQCAS RCEGSRDVGA YLFVALLRGL GLESRLVANL QCLGYSWTKL EDAESERKDG
DLRPPAADTT PKKQAKSKNH GSEKTNAKKK KPGKSAQEQS PKDAELELEY QDSDDESVVD
MQVTPVKSKS PQQAKIDADL PYANYWTEVL SPVTGNFLSI EPVVKGVVAT NRELVESLEP
RGAKADNARQ IIAYVVAYSP DGTAKDVTVR YLKRHIFPGR TKGTRYPIEK VPIYNKHGKV
RKHEHYDWFK SAMTGYRRGD KKRPITDLDE LEDDTDLKPA KPEIKPVHEG EETLQYYKQS
KEFALERHLK REEALRAGAK AVKKFQNKGK GKTEEEDVYL RSDVLNVKSA ETWHKQGRAP
LDGEEPLKRV PYRAATTNRR RELLEAEAAT GQKVLQGLYS YDQTDWIIPE PIKDGVIPRN
EYGNIDLFAE HMCPEGAVHV PFKGTVRVCK KLGINYAEAV VGFEFGHRMA VPVIQGVVIA
EENHDMVMEQ LQQDEAERAR KEDEKRRKAA LGQWRKFIMG MRIVQRIRQE YGEIDDKMSV
FGHSSKTGPA GAPEPPMMDN DENMAGGFLP EGYEEEDEGE GGDGGKPSTS HFFPTVDENE
ADDDGDLVLE HEG
//
