ID A0A168I4Y1_MUCCL Unreviewed; 1043 AA.
AC A0A168I4Y1;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=ATP-dependent RNA helicase DOB1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=MUCCIDRAFT_148342 {ECO:0000313|EMBL:OAC99554.1};
OS Mucor lusitanicus CBS 277.49.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=747725 {ECO:0000313|EMBL:OAC99554.1, ECO:0000313|Proteomes:UP000077051};
RN [1] {ECO:0000313|EMBL:OAC99554.1, ECO:0000313|Proteomes:UP000077051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 277.49 {ECO:0000313|EMBL:OAC99554.1,
RC ECO:0000313|Proteomes:UP000077051};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA Mccluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De Vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. SKI2 subfamily.
CC {ECO:0000256|ARBA:ARBA00010140}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAC99554.1}.
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DR EMBL; AMYB01000008; OAC99554.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A168I4Y1; -.
DR STRING; 747725.A0A168I4Y1; -.
DR VEuPathDB; FungiDB:QYA_148342; -.
DR OrthoDB; 1352at2759; -.
DR Proteomes; UP000077051; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR CDD; cd18024; DEXHc_Mtr4-like; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 2.40.30.300; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000077051}.
FT DOMAIN 136..292
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 402..571
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 337..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 595..622
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1043 AA; 118173 MW; 1D840208F4BFF0E0 CRC64;
MDDVEEEEVD HTDDEELITP VKRAPSAELE NEIKKQKIDV HSKEVEQFKE DVAKQVTPVV
ADSFEEETSR AVANIAGLQN APATEEGEKL VLSHAVRHQV AVPPNYPYVP ISQHKSPADP
ARVYPFTLDP FQRVAVSSIE RNESVLVAAH TSAGKTVVAE YAIAQCLKNK QRVIYTSPIK
ALSNQKYREF TEEFGDVGLM TGDVTINPQA SCLVMTTEIL RSMLYRGSEI IREVAWVVYD
EIHYMRDSER GVVWEESIIL LPDAVRFVFL SATIPNAMEF AEWICKIHEQ PCHIVYTDFR
PTPLQHYLFP AGGDGIHLVV DEKSRFREDN FQRSIAALND AKGDDPSGTQ ARGKKKGHTN
KGGKNDGPSD IYRIIKMVMM KNYHPVIVFS FSKRECESNA LQMSKLDFND ESERDMVSQV
FTNAISSLNE DDRQLPQIQQ LLPLLRRGIG VHHGGLLPIM KETIEVLFQE GLLKVLFATE
TFSIGLNMPA KTVVFTSVRK FDGKEMRWVS SGEYIQMSGR AGRRGLDERG VVIMMIDEKM
EPAVAKGMVK GESDRMNSAF HLSYNMILNL LRVEGVSPEY MLEKCFFTFQ NDSNIPQYEK
ELALLEQEKK NMVVENEEEI AAYYEIRKQI DTYTQDVRDV MNHPTYALPF LQPGRLAHIK
YDNMDFGWGV VVSCNQVKQK GKKDPEAAPE YILDVLLYCS SDSSASKDAA GHTVGIKPSP
REREGTLMAV PVSLNAIECM SHIRLNLPKK LNNKDSLNAV YKSILEIKKR FPDNIPLLDP
VTNMGIKDPA FKKLVEKIVI LEKTLLAHPL SKSDQLPVIY DKYMAKVNLI NKIKALKRKV
TDAQSIVQLE ELKNRKRVMR RLAFTTSADV VEMKGRVACE ISTGDELLLT EMIFQGVFND
LTVDQAVALL SCFVFDEKVD VKTKLQEELA APLRLMQETA KRIVKVSNEC KMNIEEQAYL
EKFKPELMDV VFAWCQGAKF SQICKMTEVY EGSLIRVFRR LEELLRQMCA AAKSIGNSEL
ENKFSEGINR IHRDIIFAAS LYL
//
