ID A0A168JGM4_9ACTN Unreviewed; 376 AA.
AC A0A168JGM4;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=IMP dehydrogenase {ECO:0000313|EMBL:OAA21118.1};
DE EC=1.1.1.205 {ECO:0000313|EMBL:OAA21118.1};
GN ORFNames=UG55_106558 {ECO:0000313|EMBL:OAA21118.1};
OS Frankia sp. EI5c.
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX NCBI_TaxID=683316 {ECO:0000313|EMBL:OAA21118.1, ECO:0000313|Proteomes:UP000077018};
RN [1] {ECO:0000313|EMBL:OAA21118.1, ECO:0000313|Proteomes:UP000077018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EI5c {ECO:0000313|EMBL:OAA21118.1,
RC ECO:0000313|Proteomes:UP000077018};
RX PubMed=27389275;
RA D'Angelo T., Oshone R., Abebe-Akele F., Simpson S., Morris K., Thomas W.K.,
RA Tisa L.S.;
RT "Permanent Draft Genome Sequence for Frankia sp. Strain EI5c, a Single-
RT Spore Isolate of a Nitrogen-Fixing Actinobacterium, Isolated from the Root
RT Nodules of Elaeagnus angustifolia.";
RL Genome Announc. 4:e00660-16(2016).
RN [2] {ECO:0000313|EMBL:OAA21118.1, ECO:0000313|Proteomes:UP000077018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EI5c {ECO:0000313|EMBL:OAA21118.1,
RC ECO:0000313|Proteomes:UP000077018};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC {ECO:0000256|ARBA:ARBA00005502}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA21118.1}.
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DR EMBL; LRTK01000065; OAA21118.1; -; Genomic_DNA.
DR RefSeq; WP_066072048.1; NZ_LRTK01000065.1.
DR AlphaFoldDB; A0A168JGM4; -.
DR STRING; 683316.UG55_106558; -.
DR PATRIC; fig|683316.3.peg.4660; -.
DR OrthoDB; 9805398at2; -.
DR Proteomes; UP000077018; Unassembled WGS sequence.
DR GO; GO:0003938; F:IMP dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR005990; IMP_DH.
DR InterPro; IPR005992; IMP_DH-rel2.
DR InterPro; IPR001093; IMP_DH_GMPRt.
DR NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR PANTHER; PTHR11911:SF85; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR Pfam; PF00478; IMPDH; 1.
DR SMART; SM01240; IMPDH; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:OAA21118.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077018}.
FT DOMAIN 17..301
FT /note="IMP dehydrogenase/GMP reductase"
FT /evidence="ECO:0000259|Pfam:PF00478"
SQ SEQUENCE 376 AA; 38493 MW; D3A34C2CCABA5EE7 CRC64;
MADVEIGIGK NARVAYGLDA VGIVPSRRTR DPADVSLGWE IDAYRFDLPI VAAAADAVTS
PASAIAMGRL GGLGVLHLEG LWTRHEDPEP LIAQVAELGA EAGAEAATRR LRELYAAPVQ
PELIGARLLQ LREAGVVTAA ALRPQKLRSL CPYVVAAGVD LLVVHGTAVS AEHLSRRTEP
LNLKQFIGQL DIPVLVGGCA SFSTALHLMR TGAAGVIVGV GGGLGDDTAS TLGIGVPLAT
AIADAAGARM RYLDESGGRY VHVIAHGDLR TGGDVAKAVA CGADAVMVDS LLAQAVDSPG
RGSSWSMEIL HSDLPRGRWS PAPASRSVAE ILTGGEGGGE DGVANIAGAL RAAMATTGYA
TLKEFQKAEI MIAAGG
//
