ID A0A171C521_9ACTN Unreviewed; 905 AA.
AC A0A171C521;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Polynucleotide kinase-phosphatase {ECO:0000313|EMBL:GAT66122.1};
GN ORFNames=PS9374_01766 {ECO:0000313|EMBL:GAT66122.1};
OS Planomonospora sphaerica.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Planomonospora.
OX NCBI_TaxID=161355 {ECO:0000313|EMBL:GAT66122.1, ECO:0000313|Proteomes:UP000077701};
RN [1] {ECO:0000313|EMBL:GAT66122.1, ECO:0000313|Proteomes:UP000077701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 9374 {ECO:0000313|EMBL:GAT66122.1,
RC ECO:0000313|Proteomes:UP000077701};
RA Dohra H., Suzuki T., Inoue Y., Kodani S.;
RT "Draft Genome Sequence of Planomonospora sphaerica JCM9374, a Rare
RT Actinomycete.";
RL Genome Announc. 4:e00779-16(2016).
RN [2] {ECO:0000313|Proteomes:UP000077701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 9374 {ECO:0000313|Proteomes:UP000077701};
RA Suzuki T., Dohra H., Kodani S.;
RT "Planomonospora sphaerica JCM9374 whole genome shotgun sequence.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAT66122.1}.
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DR EMBL; BDCX01000003; GAT66122.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A171C521; -.
DR STRING; 161355.PS9374_01766; -.
DR Proteomes; UP000077701; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd07423; MPP_Prp_like; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 3.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041780; MPP_PrpE-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR024028; PNKP_bac.
DR InterPro; IPR032380; PNKP_ligase_dom.
DR NCBIfam; TIGR04075; bacter_Pnkp; 1.
DR PANTHER; PTHR42850:SF7; BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE PRPE [ASYMMETRICAL]; 1.
DR PANTHER; PTHR42850; METALLOPHOSPHOESTERASE; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF16542; PNKP_ligase; 2.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Kinase {ECO:0000313|EMBL:GAT66122.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077701};
KW Transferase {ECO:0000313|EMBL:GAT66122.1}.
FT DOMAIN 208..397
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 489..775
FT /note="Polynucleotide kinase-phosphatase ligase"
FT /evidence="ECO:0000259|Pfam:PF16542"
FT DOMAIN 821..900
FT /note="Polynucleotide kinase-phosphatase ligase"
FT /evidence="ECO:0000259|Pfam:PF16542"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 772..824
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 905 AA; 98007 MW; 3D4C15F83A7F1A97 CRC64;
MTEENAALTG GEGPAAEAAG QEGRGGVTRI AVPEMSLVVL VGVSGSGKST FARRHFAPTQ
VVSSDFCRGL VADDENDQAA TPDAFDVLHY IVRTRLRRGL LTVVDATNVQ WEARKQLVDL
ARSENVLVDA IVLDVPEEVA IARNETRPDR DFGPQVVRRQ RKDLRRSLGK ISRDGFRRVH
VLRGADEIEA AEVVTERAWT DRRELTGPFD IIGDVHGCRA ELEALLRELG WQVGPDGATH
PEGRIAVFVG DLVDRGPDTP GVLRLVMGMV AAGTALCVSG NHEQKLARAL NGRKVRVAHG
LQESLDQLAA EPEEFRKAAL EFMDGLISHY QLDGGRLVVA HAGLKEAYHG RASGRVRSFA
LYGDTTGETD EYGLPVRYPW AREYRGRAMV VYGHTPVTEP EWVNNTICLD TGVVFGGRLT
ALRYPSREIV SVPAEKVWYE PARPLAAPGH EAGRRDPGLL SIDDVRGTRH VEVRHGGGRI
KVREENAAAA LEIMSRFAVD PRWLVYLPPT MAPPETSRLD GYLEHPAEAF AEFAAAGVRR
VVCEEKHMGS RAVAVLARTP EVAAARFGVA DGSSGAVHTR TGRPFFSDPA VAGELVDRLR
RACAPLMDEL GSDWLVLDGE LLPWSAKAEG LIRSQYASVG AAARTALPEA VAALEAAAGR
GLDVGGVLER TRRRLENAAR FRDAYARYCW PVAGLDGIRL APFQILACEG RATAVTEPHP
WHLEMLSRLD DPLIAPTRHV YADLDSAESR EAATAWWSAL TAEGGEGMVV KPVAVPGGPP
DGAGETGTGA DPGTDSGTGA DSGTAADAGA EEPPRREQAR PSRVQPGIKV RGREYLRIIY
GPDYTESLDV LRHRFLGRKR SLALREHALG LEALSRLAGG EPLWRVHEAV FAVLALESEP
VDPRL
//
