ID   A0A171C765_9ACTN        Unreviewed;       528 AA.
AC   A0A171C765;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Aminopeptidase Y {ECO:0000313|EMBL:GAT66220.1};
GN   ORFNames=PS9374_01867 {ECO:0000313|EMBL:GAT66220.1};
OS   Planomonospora sphaerica.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Planomonospora.
OX   NCBI_TaxID=161355 {ECO:0000313|EMBL:GAT66220.1, ECO:0000313|Proteomes:UP000077701};
RN   [1] {ECO:0000313|EMBL:GAT66220.1, ECO:0000313|Proteomes:UP000077701}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 9374 {ECO:0000313|EMBL:GAT66220.1,
RC   ECO:0000313|Proteomes:UP000077701};
RA   Dohra H., Suzuki T., Inoue Y., Kodani S.;
RT   "Draft Genome Sequence of Planomonospora sphaerica JCM9374, a Rare
RT   Actinomycete.";
RL   Genome Announc. 4:e00779-16(2016).
RN   [2] {ECO:0000313|Proteomes:UP000077701}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 9374 {ECO:0000313|Proteomes:UP000077701};
RA   Suzuki T., Dohra H., Kodani S.;
RT   "Planomonospora sphaerica JCM9374 whole genome shotgun sequence.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M28 family. M28A subfamily.
CC       {ECO:0000256|ARBA:ARBA00005957}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAT66220.1}.
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DR   EMBL; BDCX01000004; GAT66220.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A171C765; -.
DR   STRING; 161355.PS9374_01867; -.
DR   OrthoDB; 345880at2; -.
DR   Proteomes; UP000077701; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd03876; M28_SGAP_like; 1.
DR   CDD; cd00538; PA; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 2.
DR   InterPro; IPR045175; M28_fam.
DR   InterPro; IPR041756; M28_SGAP-like.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR003137; PA_domain.
DR   InterPro; IPR007484; Peptidase_M28.
DR   PANTHER; PTHR12147; METALLOPEPTIDASE M28 FAMILY MEMBER; 1.
DR   PANTHER; PTHR12147:SF55; PEPTIDE HYDROLASE; 1.
DR   Pfam; PF02225; PA; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   SUPFAM; SSF52025; PA domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW   ECO:0000313|EMBL:GAT66220.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022438, ECO:0000313|EMBL:GAT66220.1};
KW   Protease {ECO:0000256|ARBA:ARBA00022438, ECO:0000313|EMBL:GAT66220.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077701};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..34
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           35..528
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5007905612"
FT   DOMAIN          159..245
FT                   /note="PA"
FT                   /evidence="ECO:0000259|Pfam:PF02225"
FT   DOMAIN          268..484
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
FT   REGION          503..528
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   528 AA;  55349 MW;  03606A6E55D08DDF CRC64;
     MRLKFRRGAA RGLTVATMAT ALALPLALTT PASASTVDVP DVLATAMTYQ VKGKNVHKHL
     EKFQEIATAN GGNRAAGSPG YDASLAYVQD KLRRAGYTTS TTDVEFPLSW EEFSPAVLQQ
     TAPEAKTYTV GTDFVTVHSS GGGDVTAEVQ VVDAVIPTPE TPNTSTAGCE DADFAGFVPG
     RIALLQRGTC PFVDKATNAK EAGAAGVIFF NEGQPGRTDP LEFDIVEWRF GFPIVMASTA
     VGLDLADSPG TTVRLKVDAA TTVGRTKNLI ADSRWGKKGE IVMVGAHLDS VPEGAGINDN
     GSGSAAILET ALKLAKVPTK HKLRFAFWGA EELGLLGSEQ YVAGLSQAEK DKIRLYLNFD
     MVASPNDVTF LYDGDDSDAE GAGAGPAGSA EIEKLFEKYY AKRSLGFEGT DFDGRSDYGP
     FIANGIPSGG IFTGAEGIKT EEQAAKFGGT AGAPYDPCYH AACDGITNIN AAALERNSKA
     IAYATTFYAY DLSTIPDRNA AARAKSAAAP AAHAHAHGKD GKHAEPAK
//