ID A0A171CNE6_9ACTN Unreviewed; 745 AA.
AC A0A171CNE6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:GAT66978.1};
GN ORFNames=PS9374_02630 {ECO:0000313|EMBL:GAT66978.1};
OS Planomonospora sphaerica.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Planomonospora.
OX NCBI_TaxID=161355 {ECO:0000313|EMBL:GAT66978.1, ECO:0000313|Proteomes:UP000077701};
RN [1] {ECO:0000313|EMBL:GAT66978.1, ECO:0000313|Proteomes:UP000077701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 9374 {ECO:0000313|EMBL:GAT66978.1,
RC ECO:0000313|Proteomes:UP000077701};
RA Dohra H., Suzuki T., Inoue Y., Kodani S.;
RT "Draft Genome Sequence of Planomonospora sphaerica JCM9374, a Rare
RT Actinomycete.";
RL Genome Announc. 4:e00779-16(2016).
RN [2] {ECO:0000313|Proteomes:UP000077701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 9374 {ECO:0000313|Proteomes:UP000077701};
RA Suzuki T., Dohra H., Kodani S.;
RT "Planomonospora sphaerica JCM9374 whole genome shotgun sequence.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAT66978.1}.
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DR EMBL; BDCX01000005; GAT66978.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A171CNE6; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000077701; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 3.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000077701};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 552..572
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..626
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 647..669
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 200..329
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 725..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 745 AA; 77772 MW; A67B00405198C55F CRC64;
MSGLLGRLGG WCARRGAVVL TLWILLAAAL TAGSLLFPGP VNNNVAIPGT DAQRAHDLMR
DGFGPGYERG GTVQIVLYSA DGPLVDERRK SAVQRAVDAI RRVPHVTEVL TPYRIGGLAP
SLQIGLITVR LEGHDVSRLA ETTRALSAAA EPVRRLGIEA VPADSGTPAD KEIKTGASEV
IGVACALLVL LFAFGTLVAA MIPIFTALVS IATGLGVISL LGHLVDVPKQ ASIMATMIGL
GVGIDYALFL LSRHRKLLDD GLAVRDAVRR TAAGSGGAVV FAGGTVIIAL SALLLGGFPM
LQTLGWITGI SVVCAVLTSI TLVPALLGLL GHRVDALRLP LAGRRRPADG SSGWTGLGRW
VSRRPWRVLA LSVAVLAALT APALALKLGP LDEGYGDRGT DARRSYELMQ AGFGPGSNGP
LVVVADLREP VADREPAPAV LRTLKERVGA VEGVAHVGEP VLNSAGTAVM LQVVPEFAPS
DPRALDVVKA VRGLRIEGAS VHVGGEVAGM ADAGARIADR TPTVVGVVVL LSALLLLLAF
RSPVVAIKAA LMNLVSLGAA FGALSLVFSL GLGSGLVGMD PPAGVDMSYL TTLFFSVPID
SYIPLMLFAV LFGLSMDYEV FLLTAVRQAY LRHGDNRRAV AEGLGSTGRV ITSAALIMVS
VFVAFIAYPD PMVKIFGVGL AVAVAVDATI IRGFLVPATM VLLGRYNWWC PAWLDRILPD
LSIEGHDEED PGQDRERDLV GAARA
//
