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Database: UniProt
Entry: A0A172Q9Z1_9STRE
LinkDB: A0A172Q9Z1_9STRE
Original site: A0A172Q9Z1_9STRE 
ID   A0A172Q9Z1_9STRE        Unreviewed;       452 AA.
AC   A0A172Q9Z1;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   25-OCT-2017, entry version 13.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=A0O21_09640 {ECO:0000313|EMBL:AND80238.1};
OS   Streptococcus pantholopis.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1811193 {ECO:0000313|EMBL:AND80238.1, ECO:0000313|Proteomes:UP000077317};
RN   [1] {ECO:0000313|EMBL:AND80238.1, ECO:0000313|Proteomes:UP000077317}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TA 26 {ECO:0000313|EMBL:AND80238.1,
RC   ECO:0000313|Proteomes:UP000077317};
RA   Bai X.;
RT   "Streptococcus antelopensis sp. nov., isolated from the feces of the
RT   Tibetan antelope (Pantholops hodgsonii) in Hoh Xil National Nature
RT   Reserve, Qinghai, China.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP014699; AND80238.1; -; Genomic_DNA.
DR   RefSeq; WP_067064667.1; NZ_CP014699.1.
DR   EnsemblBacteria; AND80238; AND80238; A0O21_09640.
DR   Proteomes; UP000077317; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000077317};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077317}.
FT   DOMAIN      144    277       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      361    430       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     152    159       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   452 AA;  51733 MW;  80627B32B17E5F6D CRC64;
     MTENEQIFWN RILELAKSQL KQATYEFFVL DAKLIKIENQ VAIIYLDRMK ELFWEKNLKP
     VILTAGFEIF NAEISVEYIY DEQAAIQEEQ PVSEQSRNYT APATLAPIQS DLNPKYTFDN
     FIQGDENRWA VAASIAVANT PGTTYNPLFI WGGPGLGKTH LLNAIGNSVL QDKPNARIKY
     ITAENFINEF VVHIRLDTMD ELKEKFRNLD ILLIDDIQSL AKKTLSGTQE EFFNTFNTLH
     NHNKQIVLTS DRTPDHLNDL EQRLVTRFKW GLTVNITPPD FETRVAILTN KIQEYNFIFP
     QDTIEYLAGQ FDSNVRDLEG ALKDISLVAN FKQIDTITVD IAAEAIRARK QDSPNRITVI
     PIEEIQSQVG KFYGVTVKEI KATKRTQDIV LARQVAMFLA REMTDNSLPK IGKEFGGRDH
     STVLHAYNKI KNMISQDDGL RIEIETIKNK IK
//
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