ID A0A176JUV4_9BACT Unreviewed; 727 AA.
AC A0A176JUV4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Membrane transport protein MMPL domain-containing protein {ECO:0000259|Pfam:PF03176};
GN ORFNames=AT15_05245 {ECO:0000313|EMBL:OAA27227.1};
OS Kosmotoga arenicorallina S304.
OC Bacteria; Thermotogota; Thermotogae; Kosmotogales; Kosmotogaceae;
OC Kosmotoga.
OX NCBI_TaxID=1453497 {ECO:0000313|EMBL:OAA27227.1, ECO:0000313|Proteomes:UP000077339};
RN [1] {ECO:0000313|EMBL:OAA27227.1, ECO:0000313|Proteomes:UP000077339}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S304 {ECO:0000313|EMBL:OAA27227.1,
RC ECO:0000313|Proteomes:UP000077339};
RA Pollo S.M., Charchuk R., Nesbo C.L.;
RT "Kosmotoga genome sequencing.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA27227.1}.
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DR EMBL; JFHK01000028; OAA27227.1; -; Genomic_DNA.
DR RefSeq; WP_068349010.1; NZ_JFHK01000028.1.
DR AlphaFoldDB; A0A176JUV4; -.
DR PATRIC; fig|1453497.3.peg.1042; -.
DR OrthoDB; 9809027at2; -.
DR Proteomes; UP000077339; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000077339};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 572..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 623..642
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 663..686
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 692..715
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 43..361
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 529..718
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
SQ SEQUENCE 727 AA; 80856 MW; 794BFE7D200CADA7 CRC64;
MVKKFVELLS SKKRIFFAVL VLVNLFALFG VFRIKINPDI TTLLPSDSPA NKAYKEMEKT
FNSGEQLIFV VEIPQYDDEI EKFKALRELQ AQLEENDSIS SVNGPAPKTI FAGLRAIKLE
EITEKDIPLL KEFLSNLGEL NPLIENEKQS YASFNIFLNP DTDYRKAVKE IEDIFENSGF
VYYGSGNAFL QKKLVDYLLA IISIIPPLAA FLIVLVFRSQ IGSTKNTILS IFPAGLGALW
TIGFMGWTGK ELSILTILAP IFTIIMGSAD GIHFMAHFTD NLSKDRMGTV EKTLKGVGLP
MIMTTLTTIA GFLSLLVTGS SAMSQLAIYA SLGIGFAGIA TWIFLPLVTL NIRKFQKVEP
KPINTFLPAV ISKLWGKKVV TFAAIYLFVA VIGFRYIVIE FNQLDFFKDS TQVARSFKKV
KEINGGGIPL FAVIETTQDP LDLEIASKIL EMETKLIEEG LVSKVISVYD VMSYLNKNAY
NLDSPIYPKT SAIANLLFMM ASRQPASPLS NFLLREEHLS RMMLFPGDLK SETLQAIKDT
VTGWSNEDVQ FSVVGVPYVT KEMNDSIINK QINSMLFAVA MVFVMLLLTF RNFFVSIYAT
IPIGITLTGM FGFMGYLHIP LNITTATMAS ITIGVGIDYA IHYSSYYRMK LKNNDSSKAA
RQAFAATSKP IIANAFGLAI GMSAMFASPL KIHMFMASLM WFTMVSSSVM TLALLPTMYS
RLIRKPQ
//
