ID A0A176L7S2_9ACTN Unreviewed; 335 AA.
AC A0A176L7S2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:OAB00480.1};
GN ORFNames=A6P39_11500 {ECO:0000313|EMBL:OAB00480.1};
OS Streptomyces sp. FXJ1.172.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=710705 {ECO:0000313|EMBL:OAB00480.1};
RN [1] {ECO:0000313|EMBL:OAB00480.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FXJ1.172 {ECO:0000313|EMBL:OAB00480.1};
RA Liu M., Liu N., Shang F., Huang Y.;
RT "Activation and identification of NC-1, a novel cryptic cyclodepsipeptide
RT from red soil-derived Streptomyces sp. FXJ1.172.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAB00480.1}.
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DR EMBL; LWRP01000060; OAB00480.1; -; Genomic_DNA.
DR RefSeq; WP_067043488.1; NZ_CP119133.1.
DR AlphaFoldDB; A0A176L7S2; -.
DR STRING; 710705.A6P39_11500; -.
DR OrthoDB; 59108at2; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..58
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 306..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 335 AA; 36081 MW; BB1BBE68F4B98739 CRC64;
MSAPTIRDVA ERAGVSKSLV SLVLRGSEGV RPEKREAVLA AVEALGYRPN AAARSLSERR
TRTVGVLLND MRNPWFVELL DGLGARLHDS GLHMLMADGH LNRRLGEDLT RTFTELRVDG
LIAVGTLQDP QALRAAAGLV PTVVAGTREP VLPGVDIVAN DDEHGARLAT EHLIGLGHRH
IAHIAGQGAV GDLRRRSFEA TMREHGLAGT AVVEQGDLTE EGGYRAAVRL LSRPRRPTAV
FAVNDMTCVG ALSAAEETGL RVPLDLSLVG YDNTYLSRLR HLWLTTVDNA SRDVGRRAAQ
RLLDRMGEPD RPGEVDLTTP ILEVRGTTAP PRAGS
//
