ID A0A176U9P8_9FIRM Unreviewed; 631 AA.
AC A0A176U9P8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=HMPREF2738_00407 {ECO:0000313|EMBL:OAD89557.1};
OS Clostridiales bacterium KLE1615.
OC Bacteria; Bacillota; Clostridia; Eubacteriales.
OX NCBI_TaxID=1715004 {ECO:0000313|EMBL:OAD89557.1, ECO:0000313|Proteomes:UP000077212};
RN [1] {ECO:0000313|EMBL:OAD89557.1, ECO:0000313|Proteomes:UP000077212}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KLE1615 {ECO:0000313|EMBL:OAD89557.1,
RC ECO:0000313|Proteomes:UP000077212};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAD89557.1}.
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DR EMBL; LXPQ01000038; OAD89557.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A176U9P8; -.
DR PATRIC; fig|1715004.3.peg.405; -.
DR Proteomes; UP000077212; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:OAD89557.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077212}.
FT DOMAIN 2..134
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 140..376
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 291
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 631 AA; 73073 MW; 05D33BE6F39C3A2F CRC64;
MIRILPKPQH IEEQEGTLLL DYHCRITIED RCPRESLFYA QQLAEQIKKM TGIELGIDRR
AFGAHKGIEL CMDEEAGIPA KQTVNKEAYR LTITPDGAKV CAAQKEGLFN GVQTLRQLII
QYGVCLPCLY VEDYPELPVR GWFMDVTRGR IPKLSYLKEM ADRCSLYKIN QLHLYVEHTF
LFDGLSETWR DDTPLTAQDI LEFDEYCAER NIELVPSIAT FGHLYKVLRT KTFHELSEVE
EAEGTAFSFY ERMCHHTLNI MDERAYEFVC RLIDEYSSLF RSNLFNINCD ETFDLGKGRG
KKLADQIGSH AMYIQWVNRV CEHVKSLGKR PMFWGDIIAA HPETIRELPE DIICMTWDYS
LAPGDTNVRK LWENGAHQYL CPGVQGWNQT IHLLDIAYEN IKKMASFAHQ FDGEGLLTTD
WGDYGHLQHP ELALVGIIYG AAFGWNSKIP EREEINADIS VIEYGDRSAT LIEIISEMSN
QAVMHWGELV QFSETYRYQI AGKDMDTFWK GYLPRIETSL PHIVECNETI RNDMAKVAAL
LVQIEDDRRE GIAPVLHMAE GQILINTILR VLDREYLGHP DAYTGDTKAL AEALEIWYYE
YRRQWHKISR ESELYRIGEL IFWLADYIRE L
//
