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Database: UniProt
Entry: A0A176VAY6_9PSED
LinkDB: A0A176VAY6_9PSED
Original site: A0A176VAY6_9PSED 
ID   A0A176VAY6_9PSED        Unreviewed;       506 AA.
AC   A0A176VAY6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   05-JUL-2017, entry version 9.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=A2T76_08245 {ECO:0000313|EMBL:OAE16936.1};
OS   Pseudomonas brenneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=129817 {ECO:0000313|EMBL:OAE16936.1, ECO:0000313|Proteomes:UP000077403};
RN   [1] {ECO:0000313|EMBL:OAE16936.1, ECO:0000313|Proteomes:UP000077403}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RGCB 108 {ECO:0000313|EMBL:OAE16936.1,
RC   ECO:0000313|Proteomes:UP000077403};
RA   Dharmaprakash A., Reghunathan D., Krishnankutty S.C.,
RA   Prasannakumar M., Thomas S.;
RT   "Draft genome sequence of Pseudomonas sp. strain isolated from Arctic
RT   region producing acyl homoserine lactone molecule.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OAE16936.1}.
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DR   EMBL; LVWZ01000006; OAE16936.1; -; Genomic_DNA.
DR   EnsemblBacteria; OAE16936; OAE16936; A2T76_08245.
DR   Proteomes; UP000077403; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000077403};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077403}.
FT   DOMAIN      203    408       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      414    483       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     211    218       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   506 AA;  56784 MW;  F0190B512463A874 CRC64;
     MSVELWQQCV ELLRDELPAQ QFNTWIRPLQ VEAEGDELRV YAPNRFVLDW VNEKYLSRVL
     ELFDEHGNGM APALSLLIGS KRSSAPRAAP NAPLAAAASH AQATAASVNH APAPAAPAPS
     KSVAQKNAPM SEEPSRDSFD PMAGASSQQA PVRAEQRTVQ VEGALKHTSY LNRTFTFENF
     VEGKSNQLAR AAAWQVADNP KHGYNPLFLY GGVGLGKTHL MHAVGNHLLK KNPNAKVVYL
     HSERFVADMV KALQLNAINE FKRFYRSVDA LLIDDIQFFA RKERSQEEFF HTFNALLEGG
     QQVILTSDRY PKEIEGLEER LKSRFGWGLT VAVEPPELET RVAILMKKAD QAKVDLPHDA
     AFFIAQRIRS NVRELEGALK RVIAHSHFMG RDITIELIRE SLKDLLALQD KLVSVDNIQR
     TVAEYYKIKI SDLLSKRRSR SVARPRQVAM ALSKELTNHS LPEIGDVFGG RDHTTVLHAC
     RKINELKESD ADIREDYKNL LRTLTT
//
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