ID A0A176VVP8_MARPO Unreviewed; 1601 AA.
AC A0A176VVP8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Eukaryotic translation initiation factor 5B {ECO:0000256|ARBA:ARBA00013824};
DE AltName: Full=Translation initiation factor IF-2 {ECO:0000256|ARBA:ARBA00032478};
GN ORFNames=AXG93_4242s1090 {ECO:0000313|EMBL:OAE24837.1};
OS Marchantia polymorpha subsp. ruderalis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Marchantiophyta;
OC Marchantiopsida; Marchantiidae; Marchantiales; Marchantiaceae; Marchantia.
OX NCBI_TaxID=1480154 {ECO:0000313|EMBL:OAE24837.1, ECO:0000313|Proteomes:UP000077202};
RN [1] {ECO:0000313|EMBL:OAE24837.1, ECO:0000313|Proteomes:UP000077202}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tak-1 and cv. Tak-2 {ECO:0000313|Proteomes:UP000077202};
RC TISSUE=Whole gametophyte {ECO:0000313|EMBL:OAE24837.1};
RA Honkanen S., Jones V.A., Morieri G., Champion C., Hetherington A.J.,
RA Kelly S., Saint-Marcoux D., Proust H., Prescott H., Dolan L.;
RT "Mechanisms controlling the formation of the plant cell surface in tip-
RT growing cells are functionally conserved among land plants.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. IF-2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007733}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAE24837.1}.
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DR EMBL; LVLJ01002459; OAE24837.1; -; Genomic_DNA.
DR OrthoDB; 169393at2759; -.
DR Proteomes; UP000077202; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd03703; aeIF5B_II; 1.
DR CDD; cd16266; IF2_aeIF5B_IV; 1.
DR CDD; cd01887; IF2_eIF5B; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR InterPro; IPR029459; EFTU-type.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR015760; TIF_IF2.
DR InterPro; IPR023115; TIF_IF2_dom3.
DR InterPro; IPR036925; TIF_IF2_dom3_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43381:SF4; EUKARYOTIC TRANSLATION INITIATION FACTOR 5B; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF14578; GTP_EFTU_D4; 1.
DR Pfam; PF11987; IF-2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000077202}.
FT DOMAIN 943..1158
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 430..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 711..938
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..216
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..337
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 581..698
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..786
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 798..814
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 896..913
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 914..938
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1601 AA; 175457 MW; 01AE0A15CDBC7FC6 CRC64;
MGRKKPTSAA VDEFEPDSAS VAQAPSGNAK KGKKKGAVKV DDDEYMVEPA VEESVNGEQE
RGSGDLEADL ADQLQDLSFS GKKKTKGKNA KKAELDSSDV SFQQADETSL EEFVGGSKKK
GAKKGKKGNR VDDDEYEVSE SVDVESTPSE VPSFAEESGA GNKKKGKKGK KGTKGDDDDF
DVEISEPAIS VQSEDFGAKK KGGKKGKKGG RIDDDEYEIP ELVESEQVAP VEPEEPVFSG
KKKAGKKGKK GAKVDDDEYE LQPTIEAPAQ LDETPEPEEP IFSGKKKAAK KGKKGAKLDD
DEYELPGSNE AGSEDPMVID ELEAPKKSEK KAGKKATSTK PADLLSLLAG LDEGSVEAGD
EDAEERTAPQ STQKENGDLS GDEVVFSGKK KAKGKKAPKV IVDDEITNGG GLDANAGLRE
EASVYVEVEP EVDDEVIAFS GKKKPKKGKK EVKKDVEADD MGETAELPSL PTVSSPPVEP
SPSVTESSSS SKKNKKKGKK SGRTAQEEED LDALLAELDG PVMSKAPPKS AAPSETPAES
QPIEEQPADE VVPEAPAVAE GEEVVESAAA KKKKKKKEKE KAAKAAATEK PVDEEAAESA
KPKEEAKGKA AEKKIPKHLK AMQEQLAKIR EAEEKRKREE EERRRKEEEE QARLEELERQ
KEEAKKRRKE REKEKLLQKK KEGKLLTGKQ KEEARRLAMM REQMLAQAGI AVDSIDGAPV
DAAPAAPRKP KYDSKKKKRG PNISQQSEQA ADLTKQEISD APIEEVEEVE EVPVEVPMEV
EVAVEEEVAA PEPPPEEKSP EPEEEEEEED WDAKSFEDVA LPAIKSAFAE DEELDKRESL
VVAPVPGKST KRVVAQAPAP PAKRAASPEK RPTPAPKRGQ QPHKGPHKAA PPPAESEEEE
TESEEEEESE EEDDADTKKK RLAKDKREAR KAEALSKRSA DDLRSPICCI LGHVDTGKTK
LLDCIRRTNV QEGEAGGITQ QIGATYFPMA NIRERTKELK AVAEMRVPGL LVIDTPGHES
FTNLRARGSS LCDIAILVID IMHGLEPQTI ESLKLLQMRK TPFIVALNKV DRLYDWKSTT
NAPIRNSMKN QSKHVIQEFE TRTNQIITQL KEQGMNSELY YKNKEIRKVV SIVPTSAISG
EGVPDLLMLL VQLTQKMMEE KLMYVAEVQC TVLEVKVIEG LGTTIDVVLV NGVLHEGDQI
VVCGMQGPIV TSIRALLTPH PMKELRVKGS YEKHKELKAA QGIKITGQGL EHAIAGTQLY
VVGPEDELED IKEEAMQDMK NVMSRVDKTG EGVCVQASTL GSLEALLEFL KSPAVKIPVS
GINIGPVHKR DVMRASVMLE RKRKEYATIL AFDVKVTQEA KELADEVGVK IFTADIIYHL
FDQFTNYINT VKEEKRKETA EEAVFPCVLK LMPGCIFNKK DPIIVGVDVV EGIAKVGTPL
CIPSREFIEI GRIASMEVNH KVVDTAKKGN TVAMKIVGTN AEETQKMYGR HFDMEDEFVS
SITRKSIDLL KENYRDDLTM EDWRVKSLPD KVCEGCGGLA GIVLLVPVFC DSVRAKASLT
PELIWVDSYE SFAVGVFCSH FFVGFLFRKV NLSPCNLVLE T
//
