ID A0A177DFC8_ALTAL Unreviewed; 747 AA.
AC A0A177DFC8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=NADH-quinone oxidoreductase {ECO:0000313|EMBL:OAG17529.1};
GN ORFNames=CC77DRAFT_1052508 {ECO:0000313|EMBL:OAG17529.1};
OS Alternaria alternata (Alternaria rot fungus) (Torula alternata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Alternaria;
OC Alternaria sect. Alternaria; Alternaria alternata complex.
OX NCBI_TaxID=5599 {ECO:0000313|EMBL:OAG17529.1, ECO:0000313|Proteomes:UP000077248};
RN [1] {ECO:0000313|EMBL:OAG17529.1, ECO:0000313|Proteomes:UP000077248}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRC1lrK2f {ECO:0000313|EMBL:OAG17529.1,
RC ECO:0000313|Proteomes:UP000077248};
RG DOE Joint Genome Institute;
RA Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT ascomycete fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the complex I 75 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00005404, ECO:0000256|RuleBase:RU004523}.
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DR EMBL; KV441486; OAG17529.1; -; Genomic_DNA.
DR RefSeq; XP_018382950.1; XM_018527700.1.
DR AlphaFoldDB; A0A177DFC8; -.
DR STRING; 5599.A0A177DFC8; -.
DR GeneID; 29113294; -.
DR KEGG; aalt:CC77DRAFT_1052508; -.
DR VEuPathDB; FungiDB:CC77DRAFT_1052508; -.
DR OMA; QDQAMAY; -.
DR OrthoDB; 19999at2759; -.
DR Proteomes; UP000077248; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProt.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR CDD; cd02773; MopB_Res-Cmplx1_Nad11; 1.
DR Gene3D; 3.10.20.740; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.740; -; 2.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR000283; NADH_UbQ_OxRdtase_75kDa_su_CS.
DR InterPro; IPR010228; NADH_UbQ_OxRdtase_Gsu.
DR InterPro; IPR019574; NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd.
DR InterPro; IPR015405; NDUFS1-like_C.
DR NCBIfam; TIGR01973; NuoG; 1.
DR PANTHER; PTHR43105:SF13; NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF10588; NADH-G_4Fe-4S_3; 1.
DR Pfam; PF09326; NADH_dhqG_C; 1.
DR SMART; SM00929; NADH-G_4Fe-4S_3; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS51839; 4FE4S_HC3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00641; COMPLEX1_75K_1; 1.
DR PROSITE; PS00642; COMPLEX1_75K_2; 1.
DR PROSITE; PS00643; COMPLEX1_75K_3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000077248};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 33..111
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
FT DOMAIN 111..150
FT /note="4Fe-4S His(Cys)3-ligated-type"
FT /evidence="ECO:0000259|PROSITE:PS51839"
FT DOMAIN 250..306
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 747 AA; 82134 MW; E9F868C9E144A657 CRC64;
MLRQQMIRSL KRPAFRAALN GSRALSASAR RPADIELTID GKKVSVEAGS SLIQACDQAG
VTVPRYCYHE KLMIAGSCRM CLVEVERAPK PVASCAWPVQ PGMVVKTDSP LVHKAREGVM
EFLLANHPLD CPICDQGGEC DLQDQSMRYG ADRGRFHELE GKRAVEDKNV GPLVKTSMNR
CIHCTRCVRF SNDIAGAPEF GSFGRGNNLE IGTYLETALD TELSGNVIDL CPVGALTSKP
YAFKARPWEL YKTESIDVLD GLGSNIRVDS RGIQVMRVLP RLNDDINEEW INDKTRFACD
ALSTQRLVNP LVRVDEQFQP ATWEQALVEI GNAYKKIAPK GNEFKVVAGH LVETEALVAM
KDLANKLGSD NLALDQPGGS EPIAHGIDVR SNYAFNSRIY GVEDADYILL IGSNPRWEAA
VLNARIRKQW LRTDLEIGYV GEDFQSTFEY EKLGNNANDL KSALSGEFGK KLANAKKPMI
IVGSGVTEHV DAKSIYEQVG SFVEKNKDKF LTEEWNGYNI LQRTASRTGA YEVGFTVPSS
EVAQTKAKFV WLMGADEINE ADIPKDAFVV YQGHHGDRGA QFADVVLPGA AYTEKSVTYV
NTEGRVQMTR AAVGLPGASR EDWKIVRAAS EYLGAELPYD DVEQLRDRME EISPALRRYD
LVESASLPSL SKVQLVDQNQ GAQATGQALK NPIENFFFTD AISRNSPTMA RCSAAKAQNN
PKTNFMAPGE PYPQVGYGPQ VAAAANV
//
