ID A0A177H485_9RHOB Unreviewed; 810 AA.
AC A0A177H485;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=4-methylaminobutanoate oxidase (Formaldehyde-forming) {ECO:0000313|EMBL:OAH05765.1};
DE EC=1.5.3.19 {ECO:0000313|EMBL:OAH05765.1};
GN Name=mlr_7 {ECO:0000313|EMBL:OAH05765.1};
GN ORFNames=pfor_37c3526 {ECO:0000313|EMBL:OAH05765.1};
OS Rhodobacteraceae bacterium SB2.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae.
OX NCBI_TaxID=1689867 {ECO:0000313|EMBL:OAH05765.1, ECO:0000313|Proteomes:UP000077333};
RN [1] {ECO:0000313|EMBL:OAH05765.1, ECO:0000313|Proteomes:UP000077333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB2 {ECO:0000313|EMBL:OAH05765.1,
RC ECO:0000313|Proteomes:UP000077333};
RA Poehlein A., Billerbeck S., Voget S., Wemheuer B., Giebel H.-A.,
RA Brinkhoff T., Daniel R., Simon M.;
RT "A new prominent pelagic Roseobacter clade subcluster - CHAB-I-5:
RT biogeography and genomic comparison to other roseobacters.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAH05765.1}.
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DR EMBL; LGRT01000038; OAH05765.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A177H485; -.
DR STRING; 1689867.pfor_37c3526; -.
DR PATRIC; fig|1689867.3.peg.3570; -.
DR OrthoDB; 7156675at2; -.
DR Proteomes; UP000077333; Unassembled WGS sequence.
DR GO; GO:0102317; F:4-methylaminobutyrate oxidase (demethylating) activity; IEA:UniProtKB-EC.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR13847:SF193; PYRUVATE DEHYDROGENASE PHOSPHATASE REGULATORY SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:OAH05765.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077333}.
FT DOMAIN 9..362
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 365..420
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 422..694
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 719..802
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 810 AA; 88224 MW; E4A35F5DA53AB411 CRC64;
MTLPSSAKTL IIGGGIIGCS TAYHLAQMGE EVLLLEKAAL TSGSTWHAAG LVGQLRSNAN
ITQLLGYSID LYNKLEQETG LATGWKMNGG LRLACNEERW TEVKRQATTA HSFGLDMQLL
TPKEAQDLWP LMDISDIVGA AFLPTDGQAS PSDITQALAK GARAKGAVIK ENTPVTEILI
EGGKLAGVRT AAGDIACEKL VLCCGQWTRE LAQTIGVTVP LISVEHQYML TEAFGVPADL
PTLRDPDRLT YYKEEVGGLI MGGYEPNGIP WAKDGIPEFF DFQLLESNFD HFEQLIEMAL
PRVPKLESVG VKQLINGPES FTPDGNFILG EAPEMANVFI GAGFNAFGIA SGGGAGMALA
EWVANGAPPY DMWPVDIRRF GRPHTDVDWV RTRTLEAYGK HYTMAWPSEE HDSGRPCRRS
PLYDTLKSAG AVFGEKLGWE RPNWFAEKAE VARDIYTFER PNWHVPVGRE HKAAREAAVL
LDQSSFAKFV LQGPDAEAAL QWIAANRVDK PVGSITYTQM LNDQGGIECD VTCVRTGHDS
YYIVTGTGFA THDFDWIRRN IPDGMNAQLI DVTSSNAVLS LFGPKARNIL SAATRADVSN
EAQPFATALQ IGIAGCPVLA LRITYVGELG WELHLPTEYA LSVYNALQDA GAEHGLRNAG
YRAIETLRLE KGYRAWSSDI GPDHTPDEAG LGWAVKMKSN IAFRGREAVA AQRKEGVRKV
LATFTTSGDT ILSGRETIYR NGVRCGWLSS GGYGHTLGHS IGMGYVRASE SIDREYVLQG
TYELEVATER VSAEVTLNPL YDPGMDRVRG
//
