ID A0A177HFD8_9ACTN Unreviewed; 416 AA.
AC A0A177HFD8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Actinorhodin polyketide putative beta-ketoacyl synthase 2 {ECO:0000313|EMBL:OAH09672.1};
DE EC=2.3.1.- {ECO:0000313|EMBL:OAH09672.1};
GN ORFNames=STSP_70110 {ECO:0000313|EMBL:OAH09672.1};
OS Streptomyces jeddahensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1716141 {ECO:0000313|EMBL:OAH09672.1, ECO:0000313|Proteomes:UP000077381};
RN [1] {ECO:0000313|EMBL:OAH09672.1, ECO:0000313|Proteomes:UP000077381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G25(2015) {ECO:0000313|Proteomes:UP000077381};
RA Poehlein A., Roettig A., Hiessl S., Hauschild P., Schauer J., Madkour M.H.,
RA Al-Ansari A.M., Almakishah N.H., Steinbuechel A., Daniel R.;
RT "Genome sequence of Streptomyces sp. G25.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAH09672.1}.
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DR EMBL; LOHS01000190; OAH09672.1; -; Genomic_DNA.
DR RefSeq; WP_067284953.1; NZ_LOHS01000190.1.
DR AlphaFoldDB; A0A177HFD8; -.
DR STRING; 1716141.STSP_70110; -.
DR PATRIC; fig|1716141.3.peg.7420; -.
DR OrthoDB; 416758at2; -.
DR Proteomes; UP000077381; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR CDD; cd00832; CLF; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF322; POLYKETIDE BETA-KETOACYL SYNTHASE 2-RELATED; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:OAH09672.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077381};
KW Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:OAH09672.1}.
FT DOMAIN 6..410
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 416 AA; 43090 MW; 00FFC5D05BD63A11 CRC64;
MSSKPGRQSV ITGIGVVAPN GTTTDAFWKA TQAGTSVLDK VTREGCEHLP LRVAGEVRGF
EPADLIEETY LVQTDRFSHF AMAAADMARE DARLGRADTV DDPFAVGVVT AAGSGGGEFG
QRELQKLWGQ GSRFVGPYQS IAWFYAASTG QISIRGGFKG PCGVVASDEA GGLDALAHAA
GAIRRGTDAV VVGAAEAPLA PYSVVCQLGY EELSPSDDPA RAYRPFTTGA SGFVPAEGGA
MLVVEEATAA RDRDARARAV IAGHAATFTG ASRWEQSREG LAQAIRGALE QARCAPEDID
VVFADALGVP EADRAEALAI ADALGPHGTR VPVTAPKTGT GRAYCGAPVL DTAAAVLAME
HGLVPPTPNV FEICHDLDLV TSRARPAELR TALVLSRGLM GSNAALVLRH GTDALS
//
