ID A0A177HJ15_9ACTN Unreviewed; 421 AA.
AC A0A177HJ15;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Actinorhodin polyketide putative beta-ketoacyl synthase 1 {ECO:0000313|EMBL:OAH10971.1};
DE EC=2.3.1.- {ECO:0000313|EMBL:OAH10971.1};
GN ORFNames=STSP_58130 {ECO:0000313|EMBL:OAH10971.1};
OS Streptomyces jeddahensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1716141 {ECO:0000313|EMBL:OAH10971.1, ECO:0000313|Proteomes:UP000077381};
RN [1] {ECO:0000313|EMBL:OAH10971.1, ECO:0000313|Proteomes:UP000077381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G25(2015) {ECO:0000313|Proteomes:UP000077381};
RA Poehlein A., Roettig A., Hiessl S., Hauschild P., Schauer J., Madkour M.H.,
RA Al-Ansari A.M., Almakishah N.H., Steinbuechel A., Daniel R.;
RT "Genome sequence of Streptomyces sp. G25.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAH10971.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LOHS01000117; OAH10971.1; -; Genomic_DNA.
DR RefSeq; WP_067283720.1; NZ_LOHS01000117.1.
DR AlphaFoldDB; A0A177HJ15; -.
DR STRING; 1716141.STSP_58130; -.
DR PATRIC; fig|1716141.3.peg.6108; -.
DR OrthoDB; 9808669at2; -.
DR Proteomes; UP000077381; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:OAH10971.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077381};
KW Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:OAH10971.1}.
FT DOMAIN 1..414
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 421 AA; 43917 MW; 984E5F95224B9E55 CRC64;
MRRVVITGIG VVAPGGVGTR AFWDTLTAGR TATRGITLFD ASAFRSRIAA EADFDPAAQG
FSPAEAARLD RAAQFALVSA REAVEDSGLT SALDPVRTGV TLGSAVGCTT GLDNEYGVVS
ENGSAWEVDH TRAVAHLFDY FVPSSMAAEV AGAVGAQGPV SLVSTGCTSG IDSVCHAVDL
IREGSADVMV TGATEAPISP ITVACFDAIK ATSPRNDEPE TASRPFDRSR NGFVLGEGSA
VLVLEEFEHA RRRGAHIYAE IAGFAGRSNA YHMTGLKSDG VEMAEAIRAA LDEARLDATA
VDYVNAHGSG TKQNDRHETA AFKRSLGEHA YRVPISSIKS MIGHSLGAIG SLEVAACALA
IEHNTVPPTA NLHEADPACD LDYTPLTARE QRTDTVLSVG SGFGGFQSAI VLTRPRLQEA
A
//
