ID   A0A177HSM1_9ACTN        Unreviewed;       314 AA.
AC   A0A177HSM1;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=3,4-dihydroxyphenylacetate 2,3-dioxygenase {ECO:0000313|EMBL:OAH13599.1};
DE            EC=1.13.11.15 {ECO:0000313|EMBL:OAH13599.1};
GN   Name=hpcB {ECO:0000313|EMBL:OAH13599.1};
GN   ORFNames=STSP_29530 {ECO:0000313|EMBL:OAH13599.1};
OS   Streptomyces jeddahensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1716141 {ECO:0000313|EMBL:OAH13599.1, ECO:0000313|Proteomes:UP000077381};
RN   [1] {ECO:0000313|EMBL:OAH13599.1, ECO:0000313|Proteomes:UP000077381}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G25(2015) {ECO:0000313|Proteomes:UP000077381};
RA   Poehlein A., Roettig A., Hiessl S., Hauschild P., Schauer J., Madkour M.H.,
RA   Al-Ansari A.M., Almakishah N.H., Steinbuechel A., Daniel R.;
RT   "Genome sequence of Streptomyces sp. G25.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAH13599.1}.
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DR   EMBL; LOHS01000075; OAH13599.1; -; Genomic_DNA.
DR   RefSeq; WP_067277114.1; NZ_LOHS01000075.1.
DR   AlphaFoldDB; A0A177HSM1; -.
DR   STRING; 1716141.STSP_29530; -.
DR   PATRIC; fig|1716141.3.peg.3107; -.
DR   OrthoDB; 1676816at2; -.
DR   Proteomes; UP000077381; Unassembled WGS sequence.
DR   GO; GO:0008687; F:3,4-dihydroxyphenylacetate 2,3-dioxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008198; F:ferrous iron binding; IEA:InterPro.
DR   GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
DR   CDD; cd07370; HPCD; 1.
DR   Gene3D; 3.40.830.10; LigB-like; 1.
DR   InterPro; IPR011984; HPCD.
DR   InterPro; IPR004183; Xdiol_dOase_suB.
DR   PANTHER; PTHR30096:SF9; 4-HYDROXYPHENYLACETATE CATABOLISM PROTEIN; 1.
DR   PANTHER; PTHR30096; UNCHARACTERIZED; 1.
DR   Pfam; PF02900; LigB; 1.
DR   SUPFAM; SSF53213; LigB-like; 1.
PE   4: Predicted;
KW   Dioxygenase {ECO:0000313|EMBL:OAH13599.1};
KW   Oxidoreductase {ECO:0000313|EMBL:OAH13599.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077381}.
FT   DOMAIN          9..285
FT                   /note="Extradiol ring-cleavage dioxygenase class III enzyme
FT                   subunit B"
FT                   /evidence="ECO:0000259|Pfam:PF02900"
SQ   SEQUENCE   314 AA;  35386 MW;  57F8029B7E010023 CRC64;
     MGKIVGAGLL AHVPTIVLPE ADRLELNEGK EITLVTGLQQ LRKDVFERDD YDTVVVLDSH
     WATTVEFVVT AQQRRAGLFT SEELPRGMCR MPYDFPGDPE LAHNLASFAD KHGTWITAID
     DEYLPIYYAT INLWKFLGEG LPDKRWVTIG VCQTGDMEDH LRLGRALADG IAATPGRRVL
     LIASGALSHT FWPLRELRDH EASDPVHIRT PEAREADYER IAWFKEGRHD KVLDRMDEFW
     KYKPEAKFFH YLMMAGALGE QACTAKARQY GEYENSVGTG QVHLWFDRPA DGWTGTGLTA
     SSAPSAPRHP HSRV
//