UniProt: A0A177HTE0

Database: UniProt
Entry: A0A177HTE0_9ACTN

LinkDB:  A0A177HTE0_9ACTN 
Original site:  A0A177HTE0_9ACTN

All links

Ontology (1)   
   GO (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (18)   
   InterPro (10)   
   Pfam (3)   
   PROSITE (2)   
   SMART (3)   
All databases (21)   

Download RDF

ID   A0A177HTE0_9ACTN        Unreviewed;      3678 AA.
AC   A0A177HTE0;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=tRNA(Glu)-specific nuclease WapA {ECO:0000313|EMBL:OAH14145.1};
DE            EC=3.1.-.- {ECO:0000313|EMBL:OAH14145.1};
GN   Name=wapA_1 {ECO:0000313|EMBL:OAH14145.1};
GN   ORFNames=STSP_25950 {ECO:0000313|EMBL:OAH14145.1};
OS   Streptomyces jeddahensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1716141 {ECO:0000313|EMBL:OAH14145.1, ECO:0000313|Proteomes:UP000077381};
RN   [1] {ECO:0000313|EMBL:OAH14145.1, ECO:0000313|Proteomes:UP000077381}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G25(2015) {ECO:0000313|Proteomes:UP000077381};
RA   Poehlein A., Roettig A., Hiessl S., Hauschild P., Schauer J., Madkour M.H.,
RA   Al-Ansari A.M., Almakishah N.H., Steinbuechel A., Daniel R.;
RT   "Genome sequence of Streptomyces sp. G25.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAH14145.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LOHS01000070; OAH14145.1; -; Genomic_DNA.
DR   RefSeq; WP_067276162.1; NZ_LOHS01000070.1.
DR   STRING; 1716141.STSP_25950; -.
DR   PATRIC; fig|1716141.3.peg.2735; -.
DR   OrthoDB; 4981820at2; -.
DR   Proteomes; UP000077381; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd00081; Hint; 1.
DR   CDD; cd00110; LamG; 2.
DR   Gene3D; 2.60.120.200; -; 3.
DR   Gene3D; 3.90.930.1; -; 1.
DR   Gene3D; 1.20.120.20; Apolipoprotein; 1.
DR   Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 2.
DR   Gene3D; 2.180.10.10; RHS repeat-associated core; 3.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR045351; DUF6531.
DR   InterPro; IPR003587; Hint_dom_N.
DR   InterPro; IPR036844; Hint_dom_sf.
DR   InterPro; IPR030934; Intein_C.
DR   InterPro; IPR006558; LamG-like.
DR   InterPro; IPR001791; Laminin_G.
DR   InterPro; IPR022385; Rhs_assc_core.
DR   InterPro; IPR031325; RHS_repeat.
DR   InterPro; IPR006530; YD.
DR   NCBIfam; TIGR03696; Rhs_assc_core; 1.
DR   NCBIfam; TIGR01643; YD_repeat_2x; 10.
DR   PANTHER; PTHR32305; -; 1.
DR   PANTHER; PTHR32305:SF15; PROTEIN RHSA-RELATED; 1.
DR   Pfam; PF20148; DUF6531; 1.
DR   Pfam; PF13385; Laminin_G_3; 3.
DR   Pfam; PF05593; RHS_repeat; 8.
DR   SMART; SM00306; HintN; 1.
DR   SMART; SM00282; LamG; 2.
DR   SMART; SM00560; LamGL; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 3.
DR   SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 2.
DR   PROSITE; PS50818; INTEIN_C_TER; 1.
DR   PROSITE; PS50025; LAM_G_DOMAIN; 2.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:OAH14145.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077381};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..3678
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008063196"
FT   DOMAIN          921..1116
FT                   /note="Laminin G"
FT                   /evidence="ECO:0000259|PROSITE:PS50025"
FT   DOMAIN          1216..1404
FT                   /note="Laminin G"
FT                   /evidence="ECO:0000259|PROSITE:PS50025"
FT   DOMAIN          3496..3522
FT                   /note="Intein C-terminal splicing"
FT                   /evidence="ECO:0000259|PROSITE:PS50818"
FT   REGION          53..84
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          100..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1716..1737
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          3262..3304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          3528..3565
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..83
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        108..144
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3277..3304
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3534..3550
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3678 AA;  384425 MW;  7AA7E57F960C498C CRC64;
     MRRGIAFLVL TALAVMLTTQ QAMAQGAELD AISLPSLTSL SSWFKDPRWG KLPHQQSGTA
     AGHKHHVSAK ATEAHRGRGH APGKGRGELA AYHAHKPAVA RGKSQGAAGF NAKTSKRNAA
     KSSRTDTVFD NADGSTTRDI SPTPVNYQVR KGKWAPIDVD VRAGPDGRWH EKANSLAVDF
     ARKADDSALA SFAVDGKHSL AYGLKGAASV KGTADGSTVT YRNVLDSTDL QLTPIATGLK
     EAIVLHSADA GNTWTFPLAL KGLTPVLTKN GSVALRNAAG KTVERIPAAY AYDSKVNRRS
     GEPATTYDVT YKLLHTKSGY ALKVTLDDSW LHDPRRVFPV TVDPTVDDGW LTTYVESPDV
     QDHSFEQTIK AGSYDSGTHK AIGFSNHWDT AWDSSNATVT EAHLDIFDTW ASTCTPERFD
     VALVTQSWTP ESVTTYPGPS HGSSIGNVTP NVPNACANTA ADRQVGDWVQ VPLSTSAIQG
     WFSGTTPDYG LAVYAATTDS LHWKQFGSFN DPADGPHILV TYTGNTAPQL YEQFPSDNAV
     VNTTQPELTA WAGGANSTSG STDQYVFKVY DSTGTKVADS GLLSTGDWTV PAGKLAWNKN
     YTWTVQAYDG GLYSPADPYA MSVQVPQPVI TSGLSQNSSD HGFDASIGNY TTSDTDASIS
     TVGPSLDVER DYNSRDPRWT GAFGAGWSSI FDSRATEQYT ASGAVSSVYV TYPDGSQVGY
     GKNSDGTFTP GNGRFATFKS ITGGYSLTDK DDTVYTFTQS LGSGGYGLTS VTDANGRSIN
     LTWTSGHVTK MASAVSSRSL NLTWSTPSGA SAAHVATVVT DPVTPGNSST VQTWTYGYTG
     DQLTKVCSPL STTACTTYGY TSGSQYNNAA LDLDPHTFWP LSETSGTTAK DSVLANEGTT
     NATYENVTLG QTGPLTGSSA KAAGFNGTSS DISLPKNLGN DTDSGAISLW FKTSAGPGVL
     YSYASQPISS GQAAGFYTPS IYVGTDGKLN AEFWYSGGIN PIVSSASVAD GRWHHVVLSA
     AGNSQSLYLD NVKVGSRTGT VSIKSADAFG KNQSFNYLGT GFLGGNWPDE PHQSSTAPDG
     YPTWFNGSIA DVAWYGRPLV AADVNSLYQY GTHSASLLTS IKRPSGKTYA AMTYDAATTT
     LTQLTDENGG VWKLAAPTVS GSSQTYRGAV LGAAPSAYFR LGEAAGASTA VDEVRGGSGT
     YNGVTLGVSG PFSDQKAASF GGSSSSVTLP SGLVPGSGNE SVSMWFKTST ANGVLFSASH
     DPLSSGTTPT SYTPVLYVGS TGKLYGEFWF SGGSDNPLAS STTVTDGKWH HVVLSASAGT
     QSLYLDDALV GSQSGTAAMT NQPYTYVGAG FLGGNWPDES HHSTTDNTGY ATYFNGSIAE
     TAFYRSQLSA ADVSEQWDAA KNSTGLLPVE TVKVTSPTNA TLTYTYDVTN GNRALTETDG
     LGNKTSFGYD TGGFEHTVTD PNGAMTITGH DVRGNVVSST SCQDQAANKC STEYYTYYPD
     DTTAQLTTAD PRNDQLLTER DGRSASATDT TYLTSYTYDS AGNQTAITGP AVPGFPNGRT
     TTTVYSDGTS AYPSADGGVV PKGLPVKTIS PGGAVNTVSY FKNGDVASTT DAIGLVTSYT
     YDGLGQVLSQ KVVSDTYPNG LTTTYKYDAG GQVVEEHDPQ LTDRVTGATH AAVTTTVYDD
     DGDVTSQSVS DASGGDQART ETTTYDAYDH VLTQSDANAA EGASNGNTTT YTYDTSGNKT
     KEVTSAGVET RYTYDDNGNL LTQGLMYTGD PVAPQTATLL IESSRAYDPA GRLASVTDAM
     GNTTSYTYTD DGLTASVKRT SADGTSTYVL ESDTYDAAGN LLSSTTDNGE TVTNYKVDAA
     SRTTSTTVDP TGVDRVTTVS YTPDDEIATE NDHDSSGYDR TTTNTYDDMG NLLSETLYGD
     ASGHPAGWWK LNQTSGTNVT DASGTGNTAT AGSGVTWADD AAKFNGSSTG TGDVIATSSP
     VLDTTASYTV SAWVNLADTS TYRTFVAQGG TNRASFYLQY SKADNAFRFH AASSDATSPS
     AFYDATASSA PTLNTWTHLV GVFDATTGSM KLYVNGAQAG SATDTSPWTG TGPLSIGGTK
     TAGGTTSDVV NGEVDNVQTY QRALTASEVS SLYGKGRSGG TVGSSDEQKT TYTYDKRGLP
     TSMTDAEHNT TTYAYDEAGN LAVTTAPAVQ AEADGTNPAT VHPVTTSGFN TFGEAVEEQD
     PNGLVTTTAY DADGNKVSET LPSYTPAGAS SPNAGTTVWT YDSEGNQTSE TTPGGKTTSY
     LYDQMGNVAQ ITAPDGTKTH ATYDTNGDQL SATDATGAAS QATYDFLGRQ LTSTTLERYP
     STKTLTTTNS YAVTTGNPYG AHVASTTTPG GVTTSYGYNR AGDVTSVTDG AGNTTRYTYD
     FMGNQQKTIL PDNTWIETDY NASDDPVTTK QYDANNNLLT QTSQTYDGVG NLTSATDARG
     HTTRWTYDAA GTITQEVEPV DASTSITTTF GYDAAGNRTR FTDGRGNSWR YTYTPWGQQE
     KVIEPTTSTY SSTADSTTTF AYDADGQPTT VTQPGGVTTT MTYDANGQLK TMSGSGAEAA
     TAKRSFSYDA DGRVLSADTD VAGTAGQADY QAATHDAFTY DDRGDVLTAT GAAGSSSFTY
     NDDGSMLTRT DAAGTTSYGY DTAGRLSSLN DAATGTQLTY TYDQLNDLKT VKYGSTGQTR
     TFSYDSAHEL TGDVLVQGAS TLASFAYGYD ENGNLTSKTT TGVSGASANT YTYDWSDRLT
     SWNNGSTTTQ YAYDASGNRI RVGSDVYTYD ARDELTSDGT NTYAYSARGT MTQESSSGGS
     VAYKTDAFGD QIVAGTQSYT LDALGRNITD TDTGAQSTRT FAYSGADNTI ASDGDNTYTY
     DPAGGVIGIK PSGGTAALAL TDQHNDVVGT FTSGATGLSG SASYDPLGKV ISTSSMTGHL
     GFQSGWTEPG TGDVGTASRW YNPDTGQFLN KDSVSLDAVP NSVAANPFAY VDDNPMAGTD
     ESGNCSWYDV VCGAKKVAHK VSHAVKHVAH KVYHAVKHVA HRVVHAVKHA AHKIAHHVRD
     VYRATVRVTR RVYHYASRHV RRAYHAAVHA VHSAYHKVSH VVHRVVHAVK HVAHKVVHGV
     KKAAHAVAHA ARTAYHATVS AAKTAAKFVK HHAAAITSFV VSTAVFAGCE AATWGVGTIG
     CAALAGAAGS LVEQGFKCAQ DGGDDCSVGA FAGSAVEGAV VGAAGGKLGE LGGKLLAKVA
     PKAMKAVGGL FGKGATDAGE SAAADATDEA ASAAESEGAG TRSQSHSGDE GGSCPVPTHS
     FTGQTRVLMA DGTTKAIEKV RVGDMIANSV PGVAGTEAHK VTGVIVTYTD HDFVDLTIKK
     TAESGTESAA RAGVKAGAKS LAKKVARKAA FGLAASAAVL GALGASGHGH GDGQEPATAP
     VAAVSTASAG QDAKAAGTSG GEVEGARLTT TFHHPFYDET QTAFVEAKDL RTGDVLQTPT
     GTAEVTGVRL YHRNTTTYDL TIGSLHTYYV EAGDTPVLVH NCNGTSPRFE VDSQGETTDL
     RPEAGTRGKV GKDRTPVPLI RSGVPRGPWT LSERLSEAQG MLSDAVESVT GKLKDRTWVG
     AVNTRTGEAA VTCSGLGSCA EPNILVGTGW KAGETIFTRA FAREDLKDGL GKIWRDKEVC
     TTCQGMFPEE NFVDGVLR
//

DBGET integrated database retrieval system