ID A0A177HYF7_9ACTN Unreviewed; 1104 AA.
AC A0A177HYF7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Transcriptional regulatory protein LiaR {ECO:0000313|EMBL:OAH15845.1};
GN Name=liaR_2 {ECO:0000313|EMBL:OAH15845.1};
GN ORFNames=STSP_07760 {ECO:0000313|EMBL:OAH15845.1};
OS Streptomyces jeddahensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1716141 {ECO:0000313|EMBL:OAH15845.1, ECO:0000313|Proteomes:UP000077381};
RN [1] {ECO:0000313|EMBL:OAH15845.1, ECO:0000313|Proteomes:UP000077381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G25(2015) {ECO:0000313|Proteomes:UP000077381};
RA Poehlein A., Roettig A., Hiessl S., Hauschild P., Schauer J., Madkour M.H.,
RA Al-Ansari A.M., Almakishah N.H., Steinbuechel A., Daniel R.;
RT "Genome sequence of Streptomyces sp. G25.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAH15845.1}.
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DR EMBL; LOHS01000032; OAH15845.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A177HYF7; -.
DR STRING; 1716141.STSP_07760; -.
DR PATRIC; fig|1716141.3.peg.824; -.
DR Proteomes; UP000077381; Unassembled WGS sequence.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000077381}.
FT DOMAIN 1026..1091
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
FT REGION 84..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1104 AA; 118343 MW; D3C2721CB9E78C19 CRC64;
MRGAGEGEAA AIAAEAVSVP PAAAITAADA PALEAASRIT SAAVSEPCAM LGVVETRSVS
PVFVGRTDEL GVLNDALTRA AGRGAYSSPG TAGRGAYSSP GTAGRGAFPS SGAAGEPQGE
PQALLVGGEA GVGKTRLIEE FAARARLEGA VVAVGGCVEI GADGLPFAPF STALRALRTQ
LPDELAAATA GQEEELARLV PELGDASRRL HGRHDEEGMA RLFELTARLL ERLAADRTIV
VVLEDLHWAD ASTRHLLAYL FRTLRSGRLV VVATYRADDI HRRHPLRPLL AELDRLRSVR
RIELGRFSRD EVGRQIAGIL AQEPEPSLVD DIFERSDGNA FFVEELAVAA HEGCSPGLTD
SLRDLLLVRV EALPEHAQRV ARVAAEGGST VEYPLLAAVA GLAEDDLIEA LRAAVGATIL
LATPDGDGYR FRHALVREAV SDDLLPGERS RLNRRYAEAL EADPSLVPAD QRATRLASYW
YHAHDAAKAL PAVLRASVEA RRRHAYSEQL GLLERAMELW DAAPEDVRGE LRPVDYTEVY
PPCGCDPATT PLRYLDLMAE AAVAGRLCGE RERALKITKR ALRLLEEERD PLRSAWFWVQ
RSSLVRNQGR GDGWKELATA QDLVRGLPPS EVHADVLANV AGWSMLHEPG PDALTAAERA
VEYARMVGAR EIEMTARLTR GGLMVDAGDV EAGLAEMYAV KERVMELGVP AVIGRCHVNL
PSHLEGVGRS REAVDILKEG VEICRKLGVL DSEAWVWSNL SESLYALGRW DEAADAATRA
QRTGQSSKSR AMGATRFAYL ALARGRFAEA AHHLAAAHDH YGTHDPMPQQ SLPLSRIIIG
VAAGEGRILD ARAELDRVLA AGFPLGTQRY GWPLLLAAAT TEADARGLPV AEAGRAEVLD
RIRTAARSLA TGVPVWSAYD QWVRAELRRA EGRNAIELWA EAVEAFRPLE RPYDLARVRY
RLAEALLACG AGEEGRTEAA GLLRKSLAVA DRLGARPLAE SVALLAQRAR LTLTGDAAPA
PAVPADPADS LGLTSRERDV LRLVAVGRTN RQIAEELFIS PKTASVHVSN ILAKLGVSGR
GEAAAVAHRL RLFPDEPGDR LAAG
//
