ID A0A177Y6M3_9NOCA Unreviewed; 643 AA.
AC A0A177Y6M3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Acetoacetyl-CoA synthetase {ECO:0000313|EMBL:OAK51050.1};
GN ORFNames=A3K89_14335 {ECO:0000313|EMBL:OAK51050.1};
OS Rhodococcus kyotonensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=398843 {ECO:0000313|EMBL:OAK51050.1, ECO:0000313|Proteomes:UP000077519};
RN [1] {ECO:0000313|EMBL:OAK51050.1, ECO:0000313|Proteomes:UP000077519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KB10 {ECO:0000313|EMBL:OAK51050.1,
RC ECO:0000313|Proteomes:UP000077519};
RA Jeong H., Hong C.E., Jo S.H., Park J.M.;
RT "Genome sequence of Rhodococcus kyotonensis KB10.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAK51050.1}.
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DR EMBL; LVHI01000041; OAK51050.1; -; Genomic_DNA.
DR RefSeq; WP_068432356.1; NZ_LVHI01000041.1.
DR AlphaFoldDB; A0A177Y6M3; -.
DR Proteomes; UP000077519; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000077519}.
FT DOMAIN 36..89
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 95..461
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 527..602
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 643 AA; 70188 MW; EBC97632B431627F CRC64;
MTEPQWTPSS EDIENARITD FQRVVSERHG VDTADYRELW EWSTQNVEQF WRTVWDYFDI
QSDTEPTEVL GNSSMPGAQW FPGVQLNYVD QVRRHSDSDR TAIVHAREDG LRAELSWREL
ARQTAALART LREAGVEPGD RVVGYLPNIP EAVVAFLASA SVGAVWSACG QDYSASAALD
RLGQLDPKVL IAADGYSYGG KYHDKRGDVA VLRDGLTTVD TVIRVGDAVD GSLSWEDASA
GEGEWVSVPV AFDHPLWVVF SSGTTGLPKG IVHGHGGVLL EHLKAVALQS DIGSDDTFFW
YTSPSWMMWN FQVAGLLVGA TIVCADGSPA YPAPDALWAI TAREKVTFLG TSPGYVLSCI
KAESRPSRDH DLSALRAIGI TGSAMPASSS LWLSDNVGRD VPVFSISGGT DVVSAFAGGV
RTVPVWPGEL SAPFLGVALK AFDVDGRPVT DEVGELVVTE PMPSMPVRFW NDDGSRYREA
YFDAYPGVWR HGDWITLTAY GSVVVHGRSD STLNRNGIRM GSADIYQAVE ELPEIVESLV
LGVERGDGGY WMPLFVVLTD GTELDDALRA RINTAIREHA SPRHVPDEII AAPGVPHTRT
GKKLEVPIKR LFQGGDASRT LDRTAVDAPD LVDWYVEQGR DKR
//
