ID A0A177YK08_9NOCA Unreviewed; 558 AA.
AC A0A177YK08;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=23S rRNA methyltransferase {ECO:0000313|EMBL:OAK55877.1};
GN ORFNames=A3K89_18340 {ECO:0000313|EMBL:OAK55877.1};
OS Rhodococcus kyotonensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=398843 {ECO:0000313|EMBL:OAK55877.1, ECO:0000313|Proteomes:UP000077519};
RN [1] {ECO:0000313|EMBL:OAK55877.1, ECO:0000313|Proteomes:UP000077519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KB10 {ECO:0000313|EMBL:OAK55877.1,
RC ECO:0000313|Proteomes:UP000077519};
RA Jeong H., Hong C.E., Jo S.H., Park J.M.;
RT "Genome sequence of Rhodococcus kyotonensis KB10.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAK55877.1}.
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DR EMBL; LVHI01000007; OAK55877.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A177YK08; -.
DR Proteomes; UP000077519; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Methyltransferase {ECO:0000313|EMBL:OAK55877.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000077519};
KW Transferase {ECO:0000313|EMBL:OAK55877.1}.
FT DOMAIN 25..519
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 558 AA; 58683 MW; 3F8D31DF7B6F6456 CRC64;
MPGVEPAGTT QISGGESVTW NLHADVVIVG YGAAGVAAAL EAAEAGADVV AVDRYAGGGA
SAISGGVVYA GGGTAVQREA GVEDSVDDMY AYLAEEIGDA VTPETLRRFC DGSAATIDWL
SARGVPFSPT LCPYKTSYPS NRHYLYYSGS EAAGRFRAVA TPAPRGHRAR GKGTSGKMLF
GPLARTAKDA GVQLLPQTRV CDLLVEDGRV RGVECRTLID APERIRRVHR VLGALSAKPG
IYVPQFRYLL ERRLAHIEKK YSETVRIEAR RGVVLSAGGF VADRVMMKEH APDYTGGLAL
GTAGDDGSGI ALGAEIGAAT AKLGNVSAWR FIVPPDPFLG SLLIDGAGRR MVDESRYGAA
LGHAIVTTGR GRGWVLVDAD LAKDAAKRLP RQAMWFQRVQ NAGLRSTAVR GRTVEQVARA
AGIDPRGLRE TVDRHNAAIA SGSPDPFGKH DDFRRPIASP PFTVYDAGIP AGRALSRMMN
PCPMITLGGL VVDEDTGEVK DDAGEAIRGL YAAGRTAVGL CSNSYVSGLS LADCIFSGRR
AGINVAMGER HAVDADAH
//
