ID A0A178DGU8_9PLEO Unreviewed; 555 AA.
AC A0A178DGU8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN ORFNames=IQ07DRAFT_301626 {ECO:0000313|EMBL:OAL43258.1};
OS Pyrenochaeta sp. DS3sAY3a.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Cucurbitariaceae;
OC Pyrenochaeta.
OX NCBI_TaxID=765867 {ECO:0000313|EMBL:OAL43258.1, ECO:0000313|Proteomes:UP000077535};
RN [1] {ECO:0000313|EMBL:OAL43258.1, ECO:0000313|Proteomes:UP000077535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS3sAY3a {ECO:0000313|EMBL:OAL43258.1,
RC ECO:0000313|Proteomes:UP000077535};
RG DOE Joint Genome Institute;
RA Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT ascomycete fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the hexokinase family.
CC {ECO:0000256|ARBA:ARBA00009225, ECO:0000256|RuleBase:RU362007}.
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DR EMBL; KV441669; OAL43258.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A178DGU8; -.
DR STRING; 765867.A0A178DGU8; -.
DR InParanoid; A0A178DGU8; -.
DR OrthoDB; 5481886at2759; -.
DR UniPathway; UPA00109; UER00180.
DR Proteomes; UP000077535; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.40.367.20; -; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR001312; Hexokinase.
DR InterPro; IPR022673; Hexokinase_C.
DR InterPro; IPR022672; Hexokinase_N.
DR PANTHER; PTHR19443; HEXOKINASE; 1.
DR PANTHER; PTHR19443:SF24; HEXOKINASE YLR446W-RELATED; 1.
DR Pfam; PF00349; Hexokinase_1; 1.
DR Pfam; PF03727; Hexokinase_2; 1.
DR PRINTS; PR00475; HEXOKINASE.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS51748; HEXOKINASE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362007};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Glycolysis {ECO:0000256|RuleBase:RU362007};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU362007};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU362007};
KW Reference proteome {ECO:0000313|Proteomes:UP000077535};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU362007}.
FT DOMAIN 103..293
FT /note="Hexokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00349"
FT DOMAIN 300..550
FT /note="Hexokinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03727"
FT COILED 74..101
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 555 AA; 61808 MW; 08219DBE4FF89373 CRC64;
MPSLLLKRFK SRRVTLIPES DGTRDSPSSP PDSLKRCWYK QPMFDFWQGL LAALERIAML
PSLLHSVLPS LSSRKRARDA LRTYDRTMDD LLREIQRLFE APLESAKLQQ MSIELRRQFA
PKLQDSPICM LPSYNNTLPN GLEKGTYLAL DLGGSTFRIA LVELNGRQPG AKNMRIVTMK
SFKIDEKVRQ RRGPDFFDWM AEKIQQALAD PKLQKSTGAR SFPMGLAWSF PVEQTSSRSA
NLLDMGKGFR ATEGLLGQDL SELIMAPCRK RNLPVHMDSI VNDSSATLLS RAYEDPSTRF
AVILGTGFNI SVHLPVSSLA TTKFKGYPQK WLDEATHVLV NTECSMFGKN VFPTTRWDDQ
LNDAHVRPDF QPFEHMISGR YLGEIVRLII VEAVRTAGLF SGEMPEHLAE PYSLDTGTMA
AMEMDSSKHL TNATSLFQSK HPLKKPATYN DIQFIRQISQ LVTHRAAALL ATGIHALWVL
RTESEGLTPA NAGPTSIGCN GSVIEKYPFF RELCQSHLDE LAVASGAEPK SISLEIAVES
AIFGAAVAVC CLEGQ
//
